KIFC3 (kinesin family member C3)

2010-01-01  

Identity

HGNC
KIFC3
LOCATION
16q21
LOCUSID
3801
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3801
MIM: 604535
HGNC: 6326
Ensembl: ENSG00000140859

Variants:

dbSNP: 3801
ClinVar: 3801
TCGA: ENSG00000140859
COSMIC: KIFC3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140859ENST00000379655Q9BVG8
ENSG00000140859ENST00000421376Q9BVG8
ENSG00000140859ENST00000445690Q9BVG8
ENSG00000140859ENST00000465878Q9BVG8
ENSG00000140859ENST00000540079F5H3M2
ENSG00000140859ENST00000541240Q9BVG8
ENSG00000140859ENST00000543930B7Z896
ENSG00000140859ENST00000561524H3BMZ5
ENSG00000140859ENST00000562311H3BMR0
ENSG00000140859ENST00000562503H3BMQ3
ENSG00000140859ENST00000562903Q9BVG8
ENSG00000140859ENST00000562984H3BMJ1
ENSG00000140859ENST00000563028H3BRQ1
ENSG00000140859ENST00000564136A0A0C4DGM9
ENSG00000140859ENST00000564891H3BNZ0
ENSG00000140859ENST00000565270H3BTL6
ENSG00000140859ENST00000565397H3BUC0
ENSG00000140859ENST00000565481H3BTU1
ENSG00000140859ENST00000565684H3BPE2
ENSG00000140859ENST00000566648H3BSN2
ENSG00000140859ENST00000567059H3BTE9
ENSG00000140859ENST00000569112H3BTN1
ENSG00000140859ENST00000569222H3BV47

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Protein foldingREACTOMER-HSA-391251
Chaperonin-mediated protein foldingREACTOMER-HSA-390466
Association of TriC/CCT with target proteins during biosynthesisREACTOMER-HSA-390471

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
368900492023KIFC3 Regulates the progression and metastasis of gastric cancer via Notch1 pathway.2
368900492023KIFC3 Regulates the progression and metastasis of gastric cancer via Notch1 pathway.2
320844032020Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization.19
320844032020Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization.19
314817952019The balance between KIFC3 and EG5 tetrameric kinesins controls the onset of mitotic spindle assembly.26
314817952019The balance between KIFC3 and EG5 tetrameric kinesins controls the onset of mitotic spindle assembly.26
269545572016Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis.7
269545572016Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis.7
242758652014KIFC3 promotes mitotic progression and integrity of the central spindle in cytokinesis.2
252537212014Minus end-directed motor KIFC3 suppresses E-cadherin degradation by recruiting USP47 to adherens junctions.15
242758652014KIFC3 promotes mitotic progression and integrity of the central spindle in cytokinesis.2
252537212014Minus end-directed motor KIFC3 suppresses E-cadherin degradation by recruiting USP47 to adherens junctions.15
239544412013Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.12
239544412013Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.12
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15

Citation

Dessen P

KIFC3 (kinesin family member C3)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51312/kifc3-(kinesin-family-member-c3)