TENT4A (terminal nucleotidyltransferase 4A)

2010-02-01  

Identity

HGNC
TENT4A
LOCATION
5p15.31
LOCUSID
11044
ALIAS
LAK-1,LAK1,PAPD7,POLK,POLS,TRF4,TRF4-1,TRF41,TUTASE5
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11044
MIM: 605198
HGNC: 16705
Ensembl: ENSG00000112941

Variants:

dbSNP: 11044
ClinVar: 11044
TCGA: ENSG00000112941
COSMIC: TENT4A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112941ENST00000230859A0A0X1KG68
ENSG00000112941ENST00000515721D6RJD0
ENSG00000112941ENST00000631941Q5XG87

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018
TRAMP complexKEGGhsa_M00393
TRAMP complexKEGGM00393
DiseaseREACTOMER-HSA-1643685
Diseases of signal transductionREACTOMER-HSA-5663202
Oncogenic MAPK signalingREACTOMER-HSA-6802957
Signaling by BRAF and RAF fusionsREACTOMER-HSA-6802952

References

Pubmed IDYearTitleCitations
358677482022The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis.10
358677482022The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis.10
342034082021TENT4A Non-Canonical Poly(A) Polymerase Regulates DNA-Damage Tolerance via Multiple Pathways That Are Mutated in Endometrial Cancer.7
342034082021TENT4A Non-Canonical Poly(A) Polymerase Regulates DNA-Damage Tolerance via Multiple Pathways That Are Mutated in Endometrial Cancer.7
324514882020Viral hijacking of the TENT4-ZCCHC14 complex protects viral RNAs via mixed tailing.29
325592912020Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita.18
324514882020Viral hijacking of the TENT4-ZCCHC14 complex protects viral RNAs via mixed tailing.29
325592912020Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita.18
300263172018Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation.66
300263172018Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation.66
233760782013Molecular cloning and characterization of a novel isoform of the non-canonical poly(A) polymerase PAPD7.15
233760782013Molecular cloning and characterization of a novel isoform of the non-canonical poly(A) polymerase PAPD7.15
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.94
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.94
183309202008Discovery of genetic profiles impacting response to chemotherapy: application to gemcitabine.13

Citation

Dessen P

TENT4A (terminal nucleotidyltransferase 4A)

Atlas Genet Cytogenet Oncol Haematol. 2010-02-01

Online version: http://atlasgeneticsoncology.org/gene/51320/tent4a-(terminal-nucleotidyltransferase-4a)