NAA10 (N-alpha-acetyltransferase 10, NatA catalytic subunit)

2010-02-01  

Identity

HGNC
NAA10
LOCATION
Xq28
LOCUSID
8260
ALIAS
ARD1,ARD1A,ARD1P,DXS707,MCOPS1,NATD,OGDNS,TE2,hARD1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8260
MIM: 300013
HGNC: 18704
Ensembl: ENSG00000102030

Variants:

dbSNP: 8260
ClinVar: 8260
TCGA: ENSG00000102030
COSMIC: NAA10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102030ENST00000370009P41227
ENSG00000102030ENST00000370011C9JN83
ENSG00000102030ENST00000370015F8W808
ENSG00000102030ENST00000393712A8MWP7
ENSG00000102030ENST00000432089C9JW55
ENSG00000102030ENST00000464845P41227

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383405822024NAA10 gene expression is associated with mesenchymal transition, dedifferentiation, and progression of clear cell renal cell carcinoma.1
383405822024NAA10 gene expression is associated with mesenchymal transition, dedifferentiation, and progression of clear cell renal cell carcinoma.1
364425252023ARD1 stabilizes NRF2 through direct interaction and promotes colon cancer progression.0
368108662023Phenotypic variability and gastrointestinal manifestations/interventions for growth in NAA10-related neurodevelopmental syndrome.5
371309712023Expanding the phenotypic spectrum of NAA10-related neurodevelopmental syndrome and NAA15-related neurodevelopmental syndrome.14
372533892023NAA10 overexpression dictates distinct epigenetic, genetic, and clinicopathological characteristics in adult gliomas.3
379562232023Studying Long QT Syndrome Caused by NAA10 Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells.1
364425252023ARD1 stabilizes NRF2 through direct interaction and promotes colon cancer progression.0
368108662023Phenotypic variability and gastrointestinal manifestations/interventions for growth in NAA10-related neurodevelopmental syndrome.5
371309712023Expanding the phenotypic spectrum of NAA10-related neurodevelopmental syndrome and NAA15-related neurodevelopmental syndrome.14
372533892023NAA10 overexpression dictates distinct epigenetic, genetic, and clinicopathological characteristics in adult gliomas.3
379562232023Studying Long QT Syndrome Caused by NAA10 Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells.1
350399252022Biochemical analysis of novel NAA10 variants suggests distinct pathogenic mechanisms involving impaired protein N-terminal acetylation.11
353660562022N-α-Acetyltransferase 10 inhibits invasion and metastasis of oral squamous cell carcinoma via regulating Pirh2-p53 signalling pathway.2
364339432022Naa10p promotes cell invasiveness of esophageal cancer by coordinating the c-Myc and PAI1 regulatory axis.0

Citation

Dessen P

NAA10 (N-alpha-acetyltransferase 10, NatA catalytic subunit)

Atlas Genet Cytogenet Oncol Haematol. 2010-02-01

Online version: http://atlasgeneticsoncology.org/gene/51322/naa10-(n-alpha-acetyltransferase-10-nata-catalytic-subunit)