OLA1 (Obg like ATPase 1)

2010-02-01  

Identity

HGNC
LOCATION
2q31.1
LOCUSID
ALIAS
DOC45,GBP45,GTBP9,GTPBP9,PTD004
FUSION GENES

Other Information

Locus ID:

NCBI: 29789
MIM: 611175
HGNC: 28833
Ensembl: ENSG00000138430

Variants:

dbSNP: 29789
ClinVar: 29789
TCGA: ENSG00000138430
COSMIC: OLA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138430ENST00000284719Q9NTK5
ENSG00000138430ENST00000344357Q9NTK5
ENSG00000138430ENST00000409546J3KQ32
ENSG00000138430ENST00000427472C9JTK6
ENSG00000138430ENST00000428402Q9NTK5
ENSG00000138430ENST00000429575C9JCJ9

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
364810552023OLA1 Phosphorylation Governs the Mitochondrial Bioenergetic Function of Pulmonary Vascular Cells.5
373063522023Clinicopathological significance of  Obg-like ATPase 1 and its association with Snail in gastric cancer.0
364810552023OLA1 Phosphorylation Governs the Mitochondrial Bioenergetic Function of Pulmonary Vascular Cells.5
373063522023Clinicopathological significance of  Obg-like ATPase 1 and its association with Snail in gastric cancer.0
354400192022OLA1 promotes colorectal cancer tumorigenesis by activation of HIF1α/CA9 axis.6
354400192022OLA1 promotes colorectal cancer tumorigenesis by activation of HIF1α/CA9 axis.6
327900802021HIV p17 enhances T cell proliferation by suppressing autophagy through the p17-OLA1-GSK3β axis under nutrient starvation.3
347437502021N6-methyladenosine reader IMP2 stabilizes the ZFAS1/OLA1 axis and activates the Warburg effect: implication in colorectal cancer.50
327900802021HIV p17 enhances T cell proliferation by suppressing autophagy through the p17-OLA1-GSK3β axis under nutrient starvation.3
347437502021N6-methyladenosine reader IMP2 stabilizes the ZFAS1/OLA1 axis and activates the Warburg effect: implication in colorectal cancer.50
307424862020Cellular roles of the human Obg-like ATPase 1 (hOLA1) and its YchF homologs.7
320453672020Obg-like ATPase 1 (OLA1) overexpression predicts poor prognosis and promotes tumor progression by regulating P21/CDK2 in hepatocellular carcinoma.17
329281022020Obg-like ATPase 1 inhibited oral carcinoma cell metastasis through TGFβ/SMAD2 axis in vitro.4
307424862020Cellular roles of the human Obg-like ATPase 1 (hOLA1) and its YchF homologs.7
320453672020Obg-like ATPase 1 (OLA1) overexpression predicts poor prognosis and promotes tumor progression by regulating P21/CDK2 in hepatocellular carcinoma.17

Citation

Dessen P

OLA1 (Obg like ATPase 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-02-01

Online version: http://atlasgeneticsoncology.org/gene/51328/ola1-(obg-like-atpase-1)