MIR185 (microRNA 185)

2010-02-01  

Identity

HGNC
LOCATION
22q11.21
LOCUSID
ALIAS
MIRN185,miR-185

Other Information

Locus ID:

NCBI: 406961
MIM: 615576
HGNC: 31556
Ensembl: ENSG00000208023
miRBase:

Variants:

dbSNP: 406961
ClinVar: 406961
TCGA: ENSG00000208023
COSMIC: MIR185

RNA/Proteins

References

Pubmed IDYearTitleCitations
206036202010MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers.59
211860792011miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells.48
253193902014miR-185 suppresses tumor proliferation by directly targeting E2F6 and DNMT1 and indirectly upregulating BRCA1 in triple-negative breast cancer.44
255313242015STIM1, a direct target of microRNA-185, promotes tumor metastasis and is associated with poor prognosis in colorectal cancer.41
219622302011MiR-185 targets the DNA methyltransferases 1 and regulates global DNA methylation in human glioma.34
234172422013MicroRNA-185 suppresses proliferation, invasion, migration, and tumorigenicity of human prostate cancer cells through targeting androgen receptor.33
249113722014miR-185 inhibits hepatocellular carcinoma growth by targeting the DNMT1/PTEN/Akt pathway.33
247630542014MicroRNA-185 regulates chemotherapeutic sensitivity in gastric cancer by targeting apoptosis repressor with caspase recruitment domain.30
257009762015MicroRNA-185 inhibits cell proliferation and induces cell apoptosis by targeting VEGFA directly in von Hippel-Lindau-inactivated clear cell renal cell carcinoma.28
254489842014MiR-185 is involved in human breast carcinogenesis by targeting Vegfa.24

Citation

Dessen P

MIR185 (microRNA 185)

Atlas Genet Cytogenet Oncol Haematol. 2010-02-01

Online version: http://atlasgeneticsoncology.org/gene/51336/mir185-(microrna-185)