Identity
HGNC
LOCATION
Xp21.2
LOCUSID
ALIAS
MAP3K7IP3,NAP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 257397
MIM: 300480
HGNC: 30681
Ensembl: ENSG00000157625
Variants:
dbSNP: 257397
ClinVar: 257397
TCGA: ENSG00000157625
COSMIC: TAB3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37203408 | 2023 | miR‑27a‑3p upregulation by p65 facilitates cervical tumorigenesis by increasing TAB3 expression and is involved in the positive feedback loop of NF‑κB signaling. | 0 |
| 37203408 | 2023 | miR‑27a‑3p upregulation by p65 facilitates cervical tumorigenesis by increasing TAB3 expression and is involved in the positive feedback loop of NF‑κB signaling. | 0 |
| 32229191 | 2020 | TAB3 upregulates PIM1 expression by directly activating the TAK1-STAT3 complex to promote colorectal cancer growth. | 7 |
| 32373954 | 2020 | ZEB2-AS1 regulates the expression of TAB3 and promotes the development of colon cancer by adsorbing microRNA-188. | 4 |
| 32819610 | 2020 | Neddylation promotes protein translocation between the cytoplasm and nucleus. | 6 |
| 32229191 | 2020 | TAB3 upregulates PIM1 expression by directly activating the TAK1-STAT3 complex to promote colorectal cancer growth. | 7 |
| 32373954 | 2020 | ZEB2-AS1 regulates the expression of TAB3 and promotes the development of colon cancer by adsorbing microRNA-188. | 4 |
| 32819610 | 2020 | Neddylation promotes protein translocation between the cytoplasm and nucleus. | 6 |
| 30760523 | 2019 | G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2- and TAB1-TAB3-dependent pathway in endothelial cells. | 23 |
| 30893695 | 2019 | Evidence for a Role of TGF-β-Activated Kinase 1 and MAP3K7 Binding Protein 3 in Peanut-Specific T-Cell Responses. | 1 |
| 30760523 | 2019 | G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2- and TAB1-TAB3-dependent pathway in endothelial cells. | 23 |
| 30893695 | 2019 | Evidence for a Role of TGF-β-Activated Kinase 1 and MAP3K7 Binding Protein 3 in Peanut-Specific T-Cell Responses. | 1 |
| 30226617 | 2018 | TAB3 promotes human esophageal squamous cell carcinoma proliferation and invasion via the NF‑κB pathway. | 6 |
| 30226617 | 2018 | TAB3 promotes human esophageal squamous cell carcinoma proliferation and invasion via the NF‑κB pathway. | 6 |
| 26476534 | 2016 | TAB3 overexpression promotes cell proliferation in non-small cell lung cancer and mediates chemoresistance to CDDP in A549 cells via the NF-κB pathway. | 8 |
Citation
Dessen P
TAB3 (TGF-beta activated kinase 1 (MAP3K7) binding protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2010-02-01
Online version: http://atlasgeneticsoncology.org/gene/51346/tab3
