TSC22D3 (TSC22 domain family member 3)

2010-02-01  

Identity

HGNC
TSC22D3
LOCATION
Xq22.3
LOCUSID
1831
ALIAS
DIP,DSIPI,GILZ,TSC-22R
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1831
MIM: 300506
HGNC: 3051
Ensembl: ENSG00000157514

Variants:

dbSNP: 1831
ClinVar: 1831
TCGA: ENSG00000157514
COSMIC: TSC22D3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000157514ENST00000315660Q99576
ENSG00000157514ENST00000372382Q5JRJ0
ENSG00000157514ENST00000372383Q99576
ENSG00000157514ENST00000372384Q99576
ENSG00000157514ENST00000372390Q5JRJ2
ENSG00000157514ENST00000372397Q99576
ENSG00000157514ENST00000480691D6RDZ9
ENSG00000157514ENST00000486554D6RD92
ENSG00000157514ENST00000502650D6RAX8
ENSG00000157514ENST00000502961D6R8Z7
ENSG00000157514ENST00000503515D6R9J1
ENSG00000157514ENST00000505965D6RDZ7
ENSG00000157514ENST00000506081Q99576
ENSG00000157514ENST00000506724D6RD37
ENSG00000157514ENST00000510887D6RBL1
ENSG00000157514ENST00000514426E7EWD5
ENSG00000157514ENST00000514897D6RCK9

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
1000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Stimuli-sensing channelsREACTOMER-HSA-2672351

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
355637762022Expression Profiles of GILZ and Annexin A1 in Human Oral Candidiasis and Lichen Planus.0
365054472022Type 1 interferon suppresses expression and glucocorticoid induction of glucocorticoid-induced leucine zipper (GILZ).2
355637762022Expression Profiles of GILZ and Annexin A1 in Human Oral Candidiasis and Lichen Planus.0
365054472022Type 1 interferon suppresses expression and glucocorticoid induction of glucocorticoid-induced leucine zipper (GILZ).2
339271912021Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment.10
339271912021Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment.10
321172332020Short-Chain Alcohols Upregulate GILZ Gene Expression and Attenuate LPS-Induced Septic Immune Response.5
321503322020Glucocorticoid-transactivated TSC22D3 attenuates hypoxia- and diabetes-induced Müller glial galectin-1 expression via HIF-1α destabilization.11
322021842020MiR-222-3p ameliorates glucocorticoid-induced inhibition of airway epithelial cell repair through down-regulating GILZ expression.2
321172332020Short-Chain Alcohols Upregulate GILZ Gene Expression and Attenuate LPS-Induced Septic Immune Response.5
321503322020Glucocorticoid-transactivated TSC22D3 attenuates hypoxia- and diabetes-induced Müller glial galectin-1 expression via HIF-1α destabilization.11
322021842020MiR-222-3p ameliorates glucocorticoid-induced inhibition of airway epithelial cell repair through down-regulating GILZ expression.2
313461582019Glucocorticoid-induced leucine zipper "quantifies" stressors and increases male susceptibility to PTSD.14
314402372019Implicating the Role of GILZ in Glucocorticoid Modulation of T-Cell Activation.26
315016142019Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity.137

Citation

Dessen P

TSC22D3 (TSC22 domain family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2010-02-01

Online version: http://atlasgeneticsoncology.org/gene/51354/tsc22d3-(tsc22-domain-family-member-3)