Identity
HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
C15orf42,SLD3,Treslin
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 90381
MIM: 613298
HGNC: 28704
Ensembl: ENSG00000140534
Variants:
dbSNP: 90381
ClinVar: 90381
TCGA: ENSG00000140534
COSMIC: TICRR
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000140534 | ENST00000268138 | Q7Z2Z1 |
| ENSG00000140534 | ENST00000560985 | Q7Z2Z1 |
| ENSG00000140534 | ENST00000561095 | H0YN97 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35091422 | 2022 | Refining the domain architecture model of the replication origin firing factor Treslin/TICRR. | 5 |
| 35595754 | 2022 | Oncogenic circTICRR suppresses autophagy via binding to HuR protein and stabilizing GLUD1 mRNA in cervical cancer. | 8 |
| 36311753 | 2022 | Identification of hub genes and their correlation with infiltration of immune cells in MYCN positive neuroblastoma based on WGCNA and LASSO algorithm. | 0 |
| 35091422 | 2022 | Refining the domain architecture model of the replication origin firing factor Treslin/TICRR. | 5 |
| 35595754 | 2022 | Oncogenic circTICRR suppresses autophagy via binding to HuR protein and stabilizing GLUD1 mRNA in cervical cancer. | 8 |
| 36311753 | 2022 | Identification of hub genes and their correlation with infiltration of immune cells in MYCN positive neuroblastoma based on WGCNA and LASSO algorithm. | 0 |
| 33495413 | 2021 | Overexpression of TICRR and PPIF confer poor prognosis in endometrial cancer identified by gene co-expression network analysis. | 11 |
| 34534348 | 2021 | The CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase. | 9 |
| 33495413 | 2021 | Overexpression of TICRR and PPIF confer poor prognosis in endometrial cancer identified by gene co-expression network analysis. | 11 |
| 34534348 | 2021 | The CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase. | 9 |
| 32966791 | 2020 | Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication. | 12 |
| 32966791 | 2020 | Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication. | 12 |
| 30037903 | 2018 | Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells. | 1 |
| 30037903 | 2018 | Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells. | 1 |
| 28439015 | 2017 | Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin. | 25 |
Citation
Dessen P
TICRR (TOPBP1 interacting checkpoint and replication regulator)
Atlas Genet Cytogenet Oncol Haematol. 2010-03-01
Online version: http://atlasgeneticsoncology.org/gene/51393/ticrr-(topbp1-interacting-checkpoint-and-replication-regulator)
