MRGBP (MRG domain binding protein)

2010-03-01  

Identity

HGNC
MRGBP
LOCATION
20q13.33
LOCUSID
55257
ALIAS
C20orf20,Eaf7,MRG15BP,URCC4

Other Information

Locus ID:

NCBI: 55257
MIM: 611157
HGNC: 15866
Ensembl: ENSG00000101189

Variants:

dbSNP: 55257
ClinVar: 55257
TCGA: ENSG00000101189
COSMIC: MRGBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101189ENST00000370487Q9NV56

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
362087162022MRGBP promotes colorectal cancer metastasis via DKK1/Wnt/β-catenin and NF-kB/p65 pathways mediated EMT.3
362087162022MRGBP promotes colorectal cancer metastasis via DKK1/Wnt/β-catenin and NF-kB/p65 pathways mediated EMT.3
333549382021MRGBP, a member of the NuA4 complex, inhibits DNA double-strand break repair.4
337617152021MRGBP is a potential novel prognostic biomarker and is correlated with immune infiltrates in hepatocellular carcinoma.1
333549382021MRGBP, a member of the NuA4 complex, inhibits DNA double-strand break repair.4
337617152021MRGBP is a potential novel prognostic biomarker and is correlated with immune infiltrates in hepatocellular carcinoma.1
215353162011MRG-binding protein contributes to colorectal cancer development.9
216028932011Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma.32
215353162011MRG-binding protein contributes to colorectal cancer development.9
216028932011Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma.32
200519592010C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer.21
200519592010C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer.21
129637282003Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.116
129637282003Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.116

Citation

Dessen P

MRGBP (MRG domain binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2010-03-01

Online version: http://atlasgeneticsoncology.org/gene/51396/mrgbp-(mrg-domain-binding-protein)