Identity
HGNC
LOCATION
5q23.2
LOCUSID
ALIAS
ADLD,LMN,LMN2,LMNB,MCPH26
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4001
MIM: 150340
HGNC: 6637
Ensembl: ENSG00000113368
Variants:
dbSNP: 4001
ClinVar: 4001
TCGA: ENSG00000113368
COSMIC: LMNB1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000113368 | ENST00000261366 | P20700 |
| ENSG00000113368 | ENST00000395354 | E9PBF6 |
| ENSG00000113368 | ENST00000460265 | A0A0D9SFE5 |
| ENSG00000113368 | ENST00000492190 | A0A0D9SFY5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38224097 | 2024 | Lamin B1: a novel biomarker in adult and pediatric adrenocortical carcinoma. | 0 |
| 38265511 | 2024 | ENPP1 inhibits the transcription activity of the hepatitis B virus pregenomic promoter by upregulating the acetylation of LMNB1. | 0 |
| 38517565 | 2024 | WTAP-mediated N6-methyladenosine modification promotes the inflammation, mitochondrial damage and ferroptosis of kidney tubular epithelial cells in acute kidney injury by regulating LMNB1 expression and activating NF-κB and JAK2/STAT3 pathways. | 0 |
| 38870534 | 2024 | SUN5 interacts with nuclear membrane LaminB1 and cytoskeletal GTPase Septin12 mediating the sperm head-and-tail junction. | 0 |
| 38224097 | 2024 | Lamin B1: a novel biomarker in adult and pediatric adrenocortical carcinoma. | 0 |
| 38265511 | 2024 | ENPP1 inhibits the transcription activity of the hepatitis B virus pregenomic promoter by upregulating the acetylation of LMNB1. | 0 |
| 38517565 | 2024 | WTAP-mediated N6-methyladenosine modification promotes the inflammation, mitochondrial damage and ferroptosis of kidney tubular epithelial cells in acute kidney injury by regulating LMNB1 expression and activating NF-κB and JAK2/STAT3 pathways. | 0 |
| 38870534 | 2024 | SUN5 interacts with nuclear membrane LaminB1 and cytoskeletal GTPase Septin12 mediating the sperm head-and-tail junction. | 0 |
| 36598800 | 2023 | Differentiation-dependent changes in lamin B1 dynamics and lamin B receptor localization. | 2 |
| 37003558 | 2023 | LMNB1 deletion in ovarian cancer inhibits the proliferation and metastasis of tumor cells through PI3K/Akt pathway. | 1 |
| 37071033 | 2023 | Lamin B1 overexpression alters chromatin organization and gene expression. | 1 |
| 37229920 | 2023 | Decreased lamin A and B1 expression results in nuclear enlargement in serous ovarian carcinoma, whereas lamin A-expressing tumor cells metastasize to lymph nodes. | 0 |
| 36598800 | 2023 | Differentiation-dependent changes in lamin B1 dynamics and lamin B receptor localization. | 2 |
| 37003558 | 2023 | LMNB1 deletion in ovarian cancer inhibits the proliferation and metastasis of tumor cells through PI3K/Akt pathway. | 1 |
| 37071033 | 2023 | Lamin B1 overexpression alters chromatin organization and gene expression. | 1 |
Citation
Dessen P
LMNB1 (lamin B1)
Atlas Genet Cytogenet Oncol Haematol. 2010-04-01
Online version: http://atlasgeneticsoncology.org/gene/51411/lmnb1-(lamin-b1)
