Identity
HGNC
LOCATION
4q26
LOCUSID
ALIAS
CGB-PDE,CN5A,PDE5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8654
MIM: 603310
HGNC: 8784
Ensembl: ENSG00000138735
Variants:
dbSNP: 8654
ClinVar: 8654
TCGA: ENSG00000138735
COSMIC: PDE5A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38658954 | 2024 | CircPDE5A-encoded novel regulator of the PI3K/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated de-ubiquitination of PIK3IP1. | 0 |
| 38658954 | 2024 | CircPDE5A-encoded novel regulator of the PI3K/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated de-ubiquitination of PIK3IP1. | 0 |
| 36730555 | 2023 | LncRNA ARAP1-AS1 targets miR-516b-5p/PDE5A axis to facilitate the progression of thyroid cancer. | 1 |
| 36730555 | 2023 | LncRNA ARAP1-AS1 targets miR-516b-5p/PDE5A axis to facilitate the progression of thyroid cancer. | 1 |
| 35955722 | 2022 | Cellular Redox Metabolism Is Modulated by the Distinct Localization of Cyclic Nucleotide Phosphodiesterase 5A Isoforms. | 3 |
| 35955722 | 2022 | Cellular Redox Metabolism Is Modulated by the Distinct Localization of Cyclic Nucleotide Phosphodiesterase 5A Isoforms. | 3 |
| 33809279 | 2021 | Muscle Damage in Systemic Sclerosis and CXCL10: The Potential Therapeutic Role of PDE5 Inhibition. | 6 |
| 33952455 | 2021 | Over-expression of PDE5 in Oral Squamous Cell Carcinoma - Effect of Sildenafil Citrate. | 1 |
| 34169423 | 2021 | Influencing Factors for Erectile Dysfunction of Young Adults with No Response to PDE5i. | 0 |
| 34424768 | 2021 | Identification of a Functional PDE5A Variant at the Chromosome 4q27 Coronary Artery Disease Locus in an Extended Myocardial Infarction Family. | 4 |
| 33809279 | 2021 | Muscle Damage in Systemic Sclerosis and CXCL10: The Potential Therapeutic Role of PDE5 Inhibition. | 6 |
| 33952455 | 2021 | Over-expression of PDE5 in Oral Squamous Cell Carcinoma - Effect of Sildenafil Citrate. | 1 |
| 34169423 | 2021 | Influencing Factors for Erectile Dysfunction of Young Adults with No Response to PDE5i. | 0 |
| 34424768 | 2021 | Identification of a Functional PDE5A Variant at the Chromosome 4q27 Coronary Artery Disease Locus in an Extended Myocardial Infarction Family. | 4 |
| 31433119 | 2020 | Regulation of PDE5 expression in normal prostate, benign prostatic hyperplasia, and adenocarcinoma. | 3 |
Citation
Dessen P
PDE5A (phosphodiesterase 5A)
Atlas Genet Cytogenet Oncol Haematol. 2010-04-01
Online version: http://atlasgeneticsoncology.org/gene/51413/pde5a-(phosphodiesterase-5a)
