Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7101
MIM: 603849
HGNC: 7973
Ensembl: ENSG00000112333
Variants:
dbSNP: 7101
ClinVar: 7101
TCGA: ENSG00000112333
COSMIC: NR2E1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000112333 | ENST00000368983 | Q9Y466 |
| ENSG00000112333 | ENST00000368986 | Q9Y466 |
| ENSG00000112333 | ENST00000368986 | B6ZGT9 |
| ENSG00000112333 | ENST00000426403 | A6PVF6 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| Generic Transcription Pathway | REACTOME | R-HSA-212436 |
| Nuclear Receptor transcription pathway | REACTOME | R-HSA-383280 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36321378 | 2023 | A NR2E1-interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells. | 1 |
| 36321378 | 2023 | A NR2E1-interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells. | 1 |
| 35932893 | 2022 | The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer. | 4 |
| 35932893 | 2022 | The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer. | 4 |
| 33858847 | 2021 | Orphan nuclear receptor TLX promotes immunosuppression via its transcriptional activation of PD-L1 in glioma. | 12 |
| 34463725 | 2021 | TLX, an Orphan Nuclear Receptor With Emerging Roles in Physiology and Disease. | 4 |
| 33858847 | 2021 | Orphan nuclear receptor TLX promotes immunosuppression via its transcriptional activation of PD-L1 in glioma. | 12 |
| 34463725 | 2021 | TLX, an Orphan Nuclear Receptor With Emerging Roles in Physiology and Disease. | 4 |
| 32805587 | 2020 | Genetic analysis of the NR2E1 gene as a candidate gene of schizophrenia. | 0 |
| 32805587 | 2020 | Genetic analysis of the NR2E1 gene as a candidate gene of schizophrenia. | 0 |
| 32721119 | 2019 | Tumorigenic effects of TLX overexpression in HEK 293T cells. | 2 |
| 32721119 | 2019 | Tumorigenic effects of TLX overexpression in HEK 293T cells. | 2 |
| 27890558 | 2017 | ASK1 regulates the survival of neuroblastoma cells by interacting with TLX and stabilizing HIF-1α. | 7 |
| 27890558 | 2017 | ASK1 regulates the survival of neuroblastoma cells by interacting with TLX and stabilizing HIF-1α. | 7 |
| 26554934 | 2016 | TLX: An elusive receptor. | 3 |
Citation
Dessen P
NR2E1 (nuclear receptor subfamily 2 group E member 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-04-01
Online version: http://atlasgeneticsoncology.org/gene/51422/nr2e1-(nuclear-receptor-subfamily-2-group-e-member-1)
