Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55654
MIM: 613403
HGNC: 26038
Ensembl: ENSG00000135956
Variants:
dbSNP: 55654
ClinVar: 55654
TCGA: ENSG00000135956
COSMIC: TMEM127
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000135956 | ENST00000258439 | O75204 |
| ENSG00000135956 | ENST00000432959 | O75204 |
| ENSG00000135956 | ENST00000435268 | C9J4H2 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37659079 | 2023 | TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation. | 3 |
| 37659079 | 2023 | TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation. | 3 |
| 33051659 | 2021 | Genotype-Phenotype Features of Germline Variants of the TMEM127 Pheochromocytoma Susceptibility Gene: A 10-Year Update. | 6 |
| 33051659 | 2021 | Genotype-Phenotype Features of Germline Variants of the TMEM127 Pheochromocytoma Susceptibility Gene: A 10-Year Update. | 6 |
| 32526160 | 2020 | The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules. | 23 |
| 32575117 | 2020 | Functional Characterization of TMEM127 Variants Reveals Novel Insights into Its Membrane Topology and Trafficking. | 9 |
| 32526160 | 2020 | The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules. | 23 |
| 32575117 | 2020 | Functional Characterization of TMEM127 Variants Reveals Novel Insights into Its Membrane Topology and Trafficking. | 9 |
| 29282712 | 2018 | Homozygous TMEM127 mutations in 2 patients with bilateral pheochromocytomas. | 3 |
| 29547888 | 2018 | The TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex. | 14 |
| 29282712 | 2018 | Homozygous TMEM127 mutations in 2 patients with bilateral pheochromocytomas. | 3 |
| 29547888 | 2018 | The TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex. | 14 |
| 28384794 | 2017 | Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention. | 79 |
| 28384794 | 2017 | Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention. | 79 |
| 26960314 | 2016 | Novel SDHB and TMEM127 Mutations in Patients with Pheochromocytoma/Paraganglioma Syndrome. | 7 |
Citation
Dessen P
TMEM127 (transmembrane protein 127)
Atlas Genet Cytogenet Oncol Haematol. 2010-05-01
Online version: http://atlasgeneticsoncology.org/gene/51455/tmem127-(transmembrane-protein-127)
