TSLP (thymic stromal lymphopoietin)

2010-05-01  

Identity

HGNC
TSLP
LOCATION
5q22.1
LOCUSID
85480
ALIAS
-

Other Information

Locus ID:

NCBI: 85480
MIM: 607003
HGNC: 30743
Ensembl: ENSG00000145777

Variants:

dbSNP: 85480
ClinVar: 85480
TCGA: ENSG00000145777
COSMIC: TSLP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145777ENST00000344895Q969D9
ENSG00000145777ENST00000379706Q969D9
ENSG00000145777ENST00000420978A0A0C4DG43

Expression (GTEx)

0
1
2
3
4
5
6
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Jak-STAT signaling pathwayKEGGko04630
Cytokine-cytokine receptor interactionKEGGhsa04060
Jak-STAT signaling pathwayKEGGhsa04630

References

Pubmed IDYearTitleCitations
380815462024Airway hyperresponsiveness correlates with airway TSLP in asthma independent of eosinophilic inflammation.1
381725342024TSLP enhances progestin response in endometrial cancer via androgen receptor signal pathway.0
383967042024The Alarmin Triad-IL-25, IL-33, and TSLP-Serum Levels and Their Clinical Implications in Chronic Spontaneous Urticaria.1
384020212024TSLP is localized in and released from human lung macrophages activated by T2-high and T2-low stimuli: relevance in asthma and COPD.3
384074892024Analysis of genetic variant associated with heart failure mortality implicates thymic stromal lymphopoietin as mediator of strain-induced myocardial fibroblast-mast cell crosstalk and fibrosis.0
385579422024Relevance of Thymic Stromal Lymphopoietin on the Pathogenesis of Glioblastoma: Role of the Neutrophil.0
386302602024The role of thymic stromal lymphopoietin in cutaneous disorders.0
380815462024Airway hyperresponsiveness correlates with airway TSLP in asthma independent of eosinophilic inflammation.1
381725342024TSLP enhances progestin response in endometrial cancer via androgen receptor signal pathway.0
383967042024The Alarmin Triad-IL-25, IL-33, and TSLP-Serum Levels and Their Clinical Implications in Chronic Spontaneous Urticaria.1
384020212024TSLP is localized in and released from human lung macrophages activated by T2-high and T2-low stimuli: relevance in asthma and COPD.3
384074892024Analysis of genetic variant associated with heart failure mortality implicates thymic stromal lymphopoietin as mediator of strain-induced myocardial fibroblast-mast cell crosstalk and fibrosis.0
385579422024Relevance of Thymic Stromal Lymphopoietin on the Pathogenesis of Glioblastoma: Role of the Neutrophil.0
386302602024The role of thymic stromal lymphopoietin in cutaneous disorders.0
365172452023Plasma thymic stromal lymphopoietin (TSLP) in adults with non-severe asthma: the EGEA study.3

Citation

Dessen P

TSLP (thymic stromal lymphopoietin)

Atlas Genet Cytogenet Oncol Haematol. 2010-05-01

Online version: http://atlasgeneticsoncology.org/gene/51456/tslp-(thymic-stromal-lymphopoietin)