KIF13A (kinesin family member 13A)

2010-05-01  

Identity

HGNC
LOCATION
6p22.3
LOCUSID
ALIAS
RBKIN,bA500C11.2
FUSION GENES

Other Information

Locus ID:

NCBI: 63971
MIM: 605433
HGNC: 14566
Ensembl: ENSG00000137177

Variants:

dbSNP: 63971
ClinVar: 63971
TCGA: ENSG00000137177
COSMIC: KIF13A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137177ENST00000259711Q9H1H9
ENSG00000137177ENST00000358380H0Y307
ENSG00000137177ENST00000378814Q9H1H9
ENSG00000137177ENST00000378826Q9H1H9
ENSG00000137177ENST00000378843Q9H1H9
ENSG00000137177ENST00000502297H0Y9Z7
ENSG00000137177ENST00000502704Q9H1H9
ENSG00000137177ENST00000506044H0Y925
ENSG00000137177ENST00000636847A0A1B0GUA8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Protein foldingREACTOMER-HSA-391251
Chaperonin-mediated protein foldingREACTOMER-HSA-390466
Association of TriC/CCT with target proteins during biosynthesisREACTOMER-HSA-390471

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
202085302010PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody.86
111067282000A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex.74
198411382009AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis.74
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
244622872014Recycling endosome tubule morphogenesis from sorting endosomes requires the kinesin motor KIF13A.41
218739782011The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization.34
193285582009Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.11
290618832017KIF13A mediates trafficking of influenza A virus ribonucleoproteins.7
299806772018Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate.7
248590872014DHTP is an allosteric inhibitor of the kinesin-13 family of microtubule depolymerases.3

Citation

Dessen P

KIF13A (kinesin family member 13A)

Atlas Genet Cytogenet Oncol Haematol. 2010-05-01

Online version: http://atlasgeneticsoncology.org/gene/51469/kif13a-(kinesin-family-member-13a)