Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7023
MIM: 600743
HGNC: 11745
Ensembl: ENSG00000090447
Variants:
dbSNP: 7023
ClinVar: 7023
TCGA: ENSG00000090447
COSMIC: TFAP4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000090447 | ENST00000204517 | Q01664 |
| ENSG00000090447 | ENST00000572393 | I3L254 |
| ENSG00000090447 | ENST00000573476 | I3L301 |
| ENSG00000090447 | ENST00000574639 | I3L4L6 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Proteoglycans in cancer | KEGG | hsa05205 |
| Proteoglycans in cancer | KEGG | ko05205 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36894688 | 2023 | Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis. | 1 |
| 37610449 | 2023 | Downregulation of miR-144 blocked the proliferation and invasion of nerve cells in Hirschsprung disease by regulating Transcription Factor AP 4 (TFAP4). | 2 |
| 36894688 | 2023 | Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis. | 1 |
| 37610449 | 2023 | Downregulation of miR-144 blocked the proliferation and invasion of nerve cells in Hirschsprung disease by regulating Transcription Factor AP 4 (TFAP4). | 2 |
| 34983307 | 2022 | Upregulating microRNA-373-3p promotes apoptosis and inhibits metastasis of hepatocellular carcinoma cells. | 11 |
| 35001801 | 2022 | Inhibitory effect of CC chemokine ligand 23 (CCL23)/ transcription factor activating enhancer binding protein 4 (TFAP4) on cell proliferation, invasion and angiogenesis in hepatocellular carcinoma. | 3 |
| 35777810 | 2022 | Tribbles Pseudokinase 2 Promotes the Proliferation, Migration, and Invasion of Osteosarcoma through Modulating AP4/p21 Pathway. | 0 |
| 36074102 | 2022 | TFAP4 Activates IGF2BP1 and Promotes Progression of Non-Small Cell Lung Cancer by Stabilizing TK1 Expression through m6A Modification. | 6 |
| 34983307 | 2022 | Upregulating microRNA-373-3p promotes apoptosis and inhibits metastasis of hepatocellular carcinoma cells. | 11 |
| 35001801 | 2022 | Inhibitory effect of CC chemokine ligand 23 (CCL23)/ transcription factor activating enhancer binding protein 4 (TFAP4) on cell proliferation, invasion and angiogenesis in hepatocellular carcinoma. | 3 |
| 35777810 | 2022 | Tribbles Pseudokinase 2 Promotes the Proliferation, Migration, and Invasion of Osteosarcoma through Modulating AP4/p21 Pathway. | 0 |
| 36074102 | 2022 | TFAP4 Activates IGF2BP1 and Promotes Progression of Non-Small Cell Lung Cancer by Stabilizing TK1 Expression through m6A Modification. | 6 |
| 33373169 | 2021 | An integrated pan-cancer analysis of TFAP4 aberrations and the potential clinical implications for cancer immunity. | 17 |
| 34283887 | 2021 | Unexpected suppression of tumorigenesis by c-MYC via TFAP4-dependent restriction of stemness in B lymphocytes. | 3 |
| 33373169 | 2021 | An integrated pan-cancer analysis of TFAP4 aberrations and the potential clinical implications for cancer immunity. | 17 |
Citation
Dessen P
TFAP4 (transcription factor AP-4)
Atlas Genet Cytogenet Oncol Haematol. 2010-05-01
Online version: http://atlasgeneticsoncology.org/gene/51479/tfap4-(transcription-factor-ap-4)
