MAGEA4 (MAGE family member A4)

2003-10-01  

Identity

HGNC
MAGEA4
LOCATION
Xq28
LOCUSID
4103
ALIAS
CT1.4,MAGE-41,MAGE-X2,MAGE4,MAGE4A,MAGE4B
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4103
MIM: 300175
HGNC: 6802
Ensembl: ENSG00000147381

Variants:

dbSNP: 4103
ClinVar: 4103
TCGA: ENSG00000147381
COSMIC: MAGEA4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147381ENST00000276344P43358
ENSG00000147381ENST00000276344A0A024RC12
ENSG00000147381ENST00000360243P43358
ENSG00000147381ENST00000360243A0A024RC12
ENSG00000147381ENST00000370335P43358
ENSG00000147381ENST00000370335A0A024RC12
ENSG00000147381ENST00000370340P43358
ENSG00000147381ENST00000370340A0A024RC12
ENSG00000147381ENST00000393920P43358
ENSG00000147381ENST00000393920A0A024RC12
ENSG00000147381ENST00000393921P43358
ENSG00000147381ENST00000393921A0A024RC12
ENSG00000147381ENST00000416020C9JK50
ENSG00000147381ENST00000425182C9J9C2
ENSG00000147381ENST00000430273C9JIR1
ENSG00000147381ENST00000431963C9JZJ5
ENSG00000147381ENST00000431971C9JIR1
ENSG00000147381ENST00000441865C9JIR1
ENSG00000147381ENST00000448295C9J9C2
ENSG00000147381ENST00000457310C9JIR1

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
372666062023Involvement of NY-ESO-1 and MAGE-A4 in the pathogenesis of desmoid tumors.1
372666062023Involvement of NY-ESO-1 and MAGE-A4 in the pathogenesis of desmoid tumors.1
357362452022Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma.3
357362452022Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma.3
325328172020T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4.14
326002812020MAGE-A4, NY-ESO-1 and SAGE mRNA expression rates and co-expression relationships in solid tumours.22
325328172020T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4.14
326002812020MAGE-A4, NY-ESO-1 and SAGE mRNA expression rates and co-expression relationships in solid tumours.22
299010692018Prognostic value of MAGEA4 in primary lung cancer depends on subcellular localization and p53 status.8
301973482018Investigation of melanoma-associated antigen A4 cancer/testis antigen clinical relevance in esophageal squamous cell carcinoma.3
299010692018Prognostic value of MAGEA4 in primary lung cancer depends on subcellular localization and p53 status.8
301973482018Investigation of melanoma-associated antigen A4 cancer/testis antigen clinical relevance in esophageal squamous cell carcinoma.3
275336472017TWIST1 upregulates the MAGEA4 oncogene.18
277937762017Case-Control Study: Smoking History Affects the Production of Tumor Antigen-Specific Antibodies NY-ESO-1 in Patients with Lung Cancer in Comparison with Cancer Disease-Free Group.8
279935762017Cancer-testis antigen expression in synovial sarcoma: NY-ESO-1, PRAME, MAGEA4, and MAGEA1.40

Citation

Dessen P

MAGEA4 (MAGE family member A4)

Atlas Genet Cytogenet Oncol Haematol. 2003-10-01

Online version: http://atlasgeneticsoncology.org/gene/515/magea4-(mage-family-member-a4)