Identity
HGNC
LOCATION
2p23.1
LOCUSID
ALIAS
GALNT15,GalNac-T10,GalNac-T14
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79623
MIM: 608225
HGNC: 22946
Ensembl: ENSG00000158089
Variants:
dbSNP: 79623
ClinVar: 79623
TCGA: ENSG00000158089
COSMIC: GALNT14
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406956 | fluorouracil | Chemical | ClinicalAnnotation | associated | PD | 21635146, 31611591 | |
| PA444445 | Hepatitis C | Disease | ClinicalAnnotation | associated | PD | 31611591 | |
| PA444447 | Carcinoma, Hepatocellular | Disease | ClinicalAnnotation | associated | PD | 21635146, 31611591 | |
| PA444804 | Liver Neoplasms | Disease | ClinicalAnnotation | associated | PD | 31611591 | |
| PA445062 | Neoplasms | Disease | ClinicalAnnotation | associated | PD | 21635146, 31611591 | |
| PA449014 | cisplatin | Chemical | ClinicalAnnotation | associated | PD | 21635146, 31611591 | |
| PA450526 | mitoxantrone | Chemical | ClinicalAnnotation | associated | PD | 21635146, 31611591 | |
| PA7000 | sorafenib | Chemical | ClinicalAnnotation | associated | PD | 31611591 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34643088 | 2022 | GALNT14 regulates ferroptosis and apoptosis of ovarian cancer through the EGFR/mTOR pathway. | 24 |
| 36376274 | 2022 | GALNT14-mediated O-glycosylation on PHB2 serine-161 enhances cell growth, migration and drug resistance by activating IGF1R cascade in hepatoma cells. | 7 |
| 34643088 | 2022 | GALNT14 regulates ferroptosis and apoptosis of ovarian cancer through the EGFR/mTOR pathway. | 24 |
| 36376274 | 2022 | GALNT14-mediated O-glycosylation on PHB2 serine-161 enhances cell growth, migration and drug resistance by activating IGF1R cascade in hepatoma cells. | 7 |
| 33964375 | 2021 | GALNT2/14 overexpression correlate with prognosis and methylation: potential therapeutic targets for lung adenocarcinoma. | 11 |
| 33964375 | 2021 | GALNT2/14 overexpression correlate with prognosis and methylation: potential therapeutic targets for lung adenocarcinoma. | 11 |
| 31611591 | 2020 | A GALNT14 rs9679162 genotype-guided therapeutic strategy for advanced hepatocellular carcinoma: systemic or hepatic arterial infusion chemotherapy. | 7 |
| 31713889 | 2020 | Effects of IGFBP-3 and GalNAc-T14 on proliferation and cell cycle of glioblastoma cells and its mechanism. | 4 |
| 32098271 | 2020 | GALNT14: An Emerging Marker Capable of Predicting Therapeutic Outcomes in Multiple Cancers. | 18 |
| 31611591 | 2020 | A GALNT14 rs9679162 genotype-guided therapeutic strategy for advanced hepatocellular carcinoma: systemic or hepatic arterial infusion chemotherapy. | 7 |
| 31713889 | 2020 | Effects of IGFBP-3 and GalNAc-T14 on proliferation and cell cycle of glioblastoma cells and its mechanism. | 4 |
| 32098271 | 2020 | GALNT14: An Emerging Marker Capable of Predicting Therapeutic Outcomes in Multiple Cancers. | 18 |
| 31292201 | 2019 | BORIS Expression in Ovarian Cancer Precursor Cells Alters the CTCF Cistrome and Enhances Invasiveness through GALNT14. | 12 |
| 31292201 | 2019 | BORIS Expression in Ovarian Cancer Precursor Cells Alters the CTCF Cistrome and Enhances Invasiveness through GALNT14. | 12 |
| 29227978 | 2017 | Osterix Decreases the Chemosensitivity of Breast Cancer Cells by Upregulating GALNT14. | 4 |
Citation
Dessen P
GALNT14 (polypeptide N-acetylgalactosaminyltransferase 14)
Atlas Genet Cytogenet Oncol Haematol. 2010-06-01
Online version: http://atlasgeneticsoncology.org/gene/51524/galnt14-(polypeptide-n-acetylgalactosaminyltransferase-14)
