Identity
HGNC
LOCATION
Xq13.1
LOCUSID
ALIAS
HINCUT-1,HRNT1,MRX106,O-GLCNAC,OGT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8473
MIM: 300255
HGNC: 8127
Ensembl: ENSG00000147162
Variants:
dbSNP: 8473
ClinVar: 8473
TCGA: ENSG00000147162
COSMIC: OGT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000147162 | ENST00000373701 | O15294 |
| ENSG00000147162 | ENST00000373719 | O15294 |
| ENSG00000147162 | ENST00000444774 | C9JZL3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38345749 | 2024 | O-GlcNAcylation of TRIM29 and OGT translation forms a feedback loop to promote adaptive response of PDAC cells to glucose deficiency. | 0 |
| 38665916 | 2024 | O-GlcNAc transferase regulates collagen deposition and fibrosis resolution in idiopathic pulmonary fibrosis. | 0 |
| 38852504 | 2024 | Downregulation of O-GlcNAc transferase activity impairs basal autophagy and late endosome positioning under nutrient-rich conditions in human colon cells. | 0 |
| 38345749 | 2024 | O-GlcNAcylation of TRIM29 and OGT translation forms a feedback loop to promote adaptive response of PDAC cells to glucose deficiency. | 0 |
| 38665916 | 2024 | O-GlcNAc transferase regulates collagen deposition and fibrosis resolution in idiopathic pulmonary fibrosis. | 0 |
| 38852504 | 2024 | Downregulation of O-GlcNAc transferase activity impairs basal autophagy and late endosome positioning under nutrient-rich conditions in human colon cells. | 0 |
| 36442303 | 2023 | O-GlcNAc transferase contributes to sex-specific placental deregulation in gestational diabetes. | 6 |
| 37353617 | 2023 | Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF263. | 0 |
| 37653170 | 2023 | Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase. | 2 |
| 37907462 | 2023 | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. | 3 |
| 36442303 | 2023 | O-GlcNAc transferase contributes to sex-specific placental deregulation in gestational diabetes. | 6 |
| 37353617 | 2023 | Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF263. | 0 |
| 37653170 | 2023 | Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase. | 2 |
| 37907462 | 2023 | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. | 3 |
| 35190642 | 2022 | O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation. | 20 |
Citation
Dessen P
OGT (O-linked N-acetylglucosamine (GlcNAc) transferase)
Atlas Genet Cytogenet Oncol Haematol. 2010-06-01
Online version: http://atlasgeneticsoncology.org/gene/51541/ogt-(o-linked-n-acetylglucosamine-(glcnac)-transferase)
