BAIAP2 (BAR/IMD domain containing adaptor protein 2)

2010-07-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
BAP2,FLAF3,IRSP53,WAML
FUSION GENES

Other Information

Locus ID:

NCBI: 10458
MIM: 605475
HGNC: 947
Ensembl: ENSG00000175866

Variants:

dbSNP: 10458
ClinVar: 10458
TCGA: ENSG00000175866
COSMIC: BAIAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175866ENST00000321280Q9UQB8
ENSG00000175866ENST00000321300Q9UQB8
ENSG00000175866ENST00000416299B4DWA1
ENSG00000175866ENST00000428708Q9UQB8
ENSG00000175866ENST00000435091Q9UQB8
ENSG00000175866ENST00000571530I3L0M4
ENSG00000175866ENST00000572073I3L2M4
ENSG00000175866ENST00000572329I3L3J7
ENSG00000175866ENST00000572498I3L3C6
ENSG00000175866ENST00000572918I3L327
ENSG00000175866ENST00000573659I3L526
ENSG00000175866ENST00000573677I3L1C8
ENSG00000175866ENST00000574804I3L2J6
ENSG00000175866ENST00000575245I3L4C2
ENSG00000175866ENST00000575712Q9UQB8
ENSG00000175866ENST00000575750I3L3C5
ENSG00000175866ENST00000575841I3L4A3
ENSG00000175866ENST00000575958I3L125
ENSG00000175866ENST00000575989I3L113
ENSG00000175866ENST00000576756I3L0Y9

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Adherens junctionKEGGko04520
Regulation of actin cytoskeletonKEGGko04810
Adherens junctionKEGGhsa04520
Regulation of actin cytoskeletonKEGGhsa04810
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Fcgamma receptor (FCGR) dependent phagocytosisREACTOMER-HSA-2029480
Regulation of actin dynamics for phagocytic cup formationREACTOMER-HSA-2029482
Signal TransductionREACTOMER-HSA-162582
Signaling by VEGFREACTOMER-HSA-194138
VEGFA-VEGFR2 PathwayREACTOMER-HSA-4420097
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate WASPs and WAVEsREACTOMER-HSA-5663213

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
387246892024BIN1 regulates actin-membrane interactions during IRSp53-dependent filopodia formation.0
387246892024BIN1 regulates actin-membrane interactions during IRSp53-dependent filopodia formation.0
366983072023Actin Filaments Couple the Protrusive Tips to the Nucleus through the I-BAR Domain Protein IRSp53 during the Migration of Cells on 1D Fibers.6
366983072023Actin Filaments Couple the Protrusive Tips to the Nucleus through the I-BAR Domain Protein IRSp53 during the Migration of Cells on 1D Fibers.6
348391892022Impaired prepulse inhibition in mice with IRSp53 deletion in modulatory neurotransmitter neurons including dopamine, acetylcholine, oxytocin, and serotonin.1
348391892022Impaired prepulse inhibition in mice with IRSp53 deletion in modulatory neurotransmitter neurons including dopamine, acetylcholine, oxytocin, and serotonin.1
335060122021Insulin Receptor Substrate p53 Ameliorates High-Glucose-Induced Activation of NF-κB and Impaired Mobility of HUVECs.2
345238242021Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease.7
335060122021Insulin Receptor Substrate p53 Ameliorates High-Glucose-Induced Activation of NF-κB and Impaired Mobility of HUVECs.2
345238242021Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease.7
323887962020BAIAP2 rs8079781, postnatal smoking exposure, and emotional problems in Japanese children aged 5 years: the Kyushu Okinawa Maternal and Child Health Study.0
325352002020IRSp53 is a novel interactor of SHIP2: A role of the actin binding protein Mena in their cellular localization in breast cancer cells.2
323887962020BAIAP2 rs8079781, postnatal smoking exposure, and emotional problems in Japanese children aged 5 years: the Kyushu Okinawa Maternal and Child Health Study.0
325352002020IRSp53 is a novel interactor of SHIP2: A role of the actin binding protein Mena in their cellular localization in breast cancer cells.2
306968212019Mechanism of IRSp53 inhibition by 14-3-3.26

Citation

Dessen P

BAIAP2 (BAR/IMD domain containing adaptor protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2010-07-01

Online version: http://atlasgeneticsoncology.org/gene/51548/baiap2-(bar-imd-domain-containing-adaptor-protein-2)