RPL41 (ribosomal protein L41)

2010-07-01  

Identity

HGNC
LOCATION
12q13.2
LOCUSID
ALIAS
L41
FUSION GENES

Other Information

Locus ID:

NCBI: 6171
MIM: 613315
HGNC: 10354
Ensembl: ENSG00000229117

Variants:

dbSNP: 6171
ClinVar: 6171
TCGA: ENSG00000229117
COSMIC: RPL41

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000229117ENST00000501597P62945
ENSG00000229117ENST00000546591P62945

Expression (GTEx)

0
500
1000
1500
2000

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Ribosome, eukaryotesKEGGhsa_M00177
Ribosome, eukaryotesKEGGM00177
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
Eukaryotic Translation InitiationREACTOMER-HSA-72613
Cap-dependent Translation InitiationREACTOMER-HSA-72737
Formation of a pool of free 40S subunitsREACTOMER-HSA-72689
GTP hydrolysis and joining of the 60S ribosomal subunitREACTOMER-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expressionREACTOMER-HSA-156827
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Eukaryotic Translation ElongationREACTOMER-HSA-156842
Peptide chain elongationREACTOMER-HSA-156902
Eukaryotic Translation TerminationREACTOMER-HSA-72764
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
Influenza InfectionREACTOMER-HSA-168254
Influenza Life CycleREACTOMER-HSA-168255
Influenza Viral RNA Transcription and ReplicationREACTOMER-HSA-168273
Viral mRNA TranslationREACTOMER-HSA-192823
Gene ExpressionREACTOMER-HSA-74160
Nonsense-Mediated Decay (NMD)REACTOMER-HSA-927802
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)REACTOMER-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)REACTOMER-HSA-975956
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Selenoamino acid metabolismREACTOMER-HSA-2408522
Selenocysteine synthesisREACTOMER-HSA-2408557
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
327832562021RPL41 sensitizes retinoblastoma cells to chemotherapeutic drugs via ATF4 degradation.5
327832562021RPL41 sensitizes retinoblastoma cells to chemotherapeutic drugs via ATF4 degradation.5
270827022016Overexpression of PDZK1IP1, EEF1A2 and RPL41 genes in intrahepatic cholangiocarcinoma.1
270827022016Overexpression of PDZK1IP1, EEF1A2 and RPL41 genes in intrahepatic cholangiocarcinoma.1
217064772011Ribosomal protein RPL41 induces rapid degradation of ATF4, a transcription factor critical for tumour cell survival in stress.19
217064772011Ribosomal protein RPL41 induces rapid degradation of ATF4, a transcription factor critical for tumour cell survival in stress.19
202348222010RPL41, a small ribosomal peptide deregulated in tumors, is essential for mitosis and centrosome integrity.14
202348222010RPL41, a small ribosomal peptide deregulated in tumors, is essential for mitosis and centrosome integrity.14

Citation

Dessen P

RPL41 (ribosomal protein L41)

Atlas Genet Cytogenet Oncol Haematol. 2010-07-01

Online version: http://atlasgeneticsoncology.org/gene/51552/rpl41-(ribosomal-protein-l41)