Identity
HGNC
LOCATION
1p13.1
LOCUSID
ALIAS
CMT2DD,HOMGSMR2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 476
MIM: 182310
HGNC: 799
Ensembl: ENSG00000163399
Variants:
dbSNP: 476
ClinVar: 476
TCGA: ENSG00000163399
COSMIC: ATP1A1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA162409589 | ZEB1 | Gene | Pathway | associated | 23788015 | ||
| PA164749044 | eplerenone | Chemical | Pathway | associated | 23788015 | ||
| PA30616 | MAPK1 | Gene | Pathway | associated | 23788015 | ||
| PA30622 | MAPK3 | Gene | Pathway | associated | 23788015 | ||
| PA31 | ADD1 | Gene | Pathway | associated | 23788015 | ||
| PA31534 | NEDD4L | Gene | Pathway | associated | 23788015 | ||
| PA33663 | PPP2CA | Gene | Pathway | associated | 23788015 | ||
| PA33745 | PRKAA2 | Gene | Pathway | associated | 23788015 | ||
| PA33765 | PRKCE | Gene | Pathway | associated | 23788015 | ||
| PA40 | GRK2 | Gene | Pathway | associated | 23788015 | ||
| PA41 | GRK3 | Gene | Pathway | associated | 23788015 | ||
| PA60 | ARRB2 | Gene | Pathway | associated | 23788015 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37659504 | 2024 | ATP1A1-linked diseases require a malfunctioning protein product from one allele. | 0 |
| 37904054 | 2024 | ATP1A1/BCL2L1 predicts the response of myelomonocytic and monocytic acute myeloid leukemia to cardiac glycosides. | 0 |
| 37659504 | 2024 | ATP1A1-linked diseases require a malfunctioning protein product from one allele. | 0 |
| 37904054 | 2024 | ATP1A1/BCL2L1 predicts the response of myelomonocytic and monocytic acute myeloid leukemia to cardiac glycosides. | 0 |
| 36763655 | 2023 | Na, K-ATPase α1 cooperates with its endogenous ligand to reprogram immune microenvironment of lung carcinoma and promotes immune escape. | 2 |
| 36871182 | 2023 | Meta-data analysis of kidney stone disease highlights ATP1A1 involvement in renal crystal formation. | 0 |
| 37407874 | 2023 | Functional Analysis and Clinical Importance of ATP1A1 in Colon Cancer. | 0 |
| 37566922 | 2023 | Silencing of ATP1A1 attenuates cell membrane disruption by nanosecond electric pulses. | 0 |
| 37830582 | 2023 | Normalization of the ATP1A1 Signalosome Rescinds Epigenetic Modifications and Induces Cell Autophagy in Hepatocellular Carcinoma. | 0 |
| 36763655 | 2023 | Na, K-ATPase α1 cooperates with its endogenous ligand to reprogram immune microenvironment of lung carcinoma and promotes immune escape. | 2 |
| 36871182 | 2023 | Meta-data analysis of kidney stone disease highlights ATP1A1 involvement in renal crystal formation. | 0 |
| 37407874 | 2023 | Functional Analysis and Clinical Importance of ATP1A1 in Colon Cancer. | 0 |
| 37566922 | 2023 | Silencing of ATP1A1 attenuates cell membrane disruption by nanosecond electric pulses. | 0 |
| 37830582 | 2023 | Normalization of the ATP1A1 Signalosome Rescinds Epigenetic Modifications and Induces Cell Autophagy in Hepatocellular Carcinoma. | 0 |
| 35110381 | 2022 | De Novo ATP1A1 Variants in an Early-Onset Complex Neurodevelopmental Syndrome. | 5 |
Citation
Dessen P
ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-07-01
Online version: http://atlasgeneticsoncology.org/gene/51554/atp1a1-(atpase-na+-k+-transporting-subunit-alpha-1)
