EMILIN2 (elastin microfibril interfacer 2)

2010-07-01  

Identity

HGNC
LOCATION
18p11.32
LOCUSID
ALIAS
EMILIN-2,FOAP-10
FUSION GENES

Other Information

Locus ID:

NCBI: 84034
MIM: 608928
HGNC: 19881
Ensembl: ENSG00000132205

Variants:

dbSNP: 84034
ClinVar: 84034
TCGA: ENSG00000132205
COSMIC: EMILIN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132205ENST00000254528Q9BXX0

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
176985842007Regulation of the extrinsic apoptotic pathway by the extracellular matrix glycoprotein EMILIN2.29
203609402010The extracellular matrix glycoprotein elastin microfibril interface located protein 2: a dual role in the tumor microenvironment.16
243748072014EMILIN2 down-modulates the Wnt signalling pathway and suppresses breast cancer cell growth and migration.12
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
294836442018The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth.9
179888452008EMILINs interact with anthrax protective antigen and inhibit toxin action in vitro.8
305449092018Loss of Multimerin-2 and EMILIN-2 Expression in Gastric Cancer Associate with Altered Angiogenesis.4
254456272015Multiple-interactions among EMILIN1 and EMILIN2 N- and C-terminal domains.3

Citation

Dessen P

EMILIN2 (elastin microfibril interfacer 2)

Atlas Genet Cytogenet Oncol Haematol. 2010-07-01

Online version: http://atlasgeneticsoncology.org/gene/51561/emilin2-(elastin-microfibril-interfacer-2)