MIR17HG (miR-17-92a-1 cluster host gene)

2010-08-01  

Identity

HGNC
LOCATION
13q31.3
LOCUSID
ALIAS
C13orf25,FGLDS2,LINC00048,MIHG1,MIRH1,MIRHG1,NCRNA00048,miR-17-92

Other Information

Locus ID:

NCBI: 407975
MIM: 609415
HGNC: 23564
Ensembl: ENSG00000215417

Variants:

dbSNP: 407975
ClinVar: 407975
TCGA: ENSG00000215417
COSMIC: MIR17HG

RNA/Proteins

Expression (GTEx)

0
1
2
3
4
5
6
7

References

Pubmed IDYearTitleCitations
196967422009Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis.125
203056912010De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures.66
221165522012The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation.62
234386032013The c-Myc-regulated microRNA-17~92 (miR-17~92) and miR-106a~363 clusters target hCYP19A1 and hGCM1 to inhibit human trophoblast differentiation.51
218973632011Epigenetic silencing of the oncogenic miR-17-92 cluster during PU.1-directed macrophage differentiation.47
235327562013c-Myc-mediated overexpression of miR-17-92 suppresses replication of hepatitis B virus in human hepatoma cells.34
195974732009Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers.33
241698262013The Myc-miR-17-92 axis amplifies B-cell receptor signaling via inhibition of ITIM proteins: a novel lymphomagenic feed-forward loop.29
232881732013Histone deacetylase 9 promotes angiogenesis by targeting the antiangiogenic microRNA-17-92 cluster in endothelial cells.27
252395652014miR-17-92 cluster promotes cholangiocarcinoma growth: evidence for PTEN as downstream target and IL-6/Stat3 as upstream activator.27

Citation

Dessen P

MIR17HG (miR-17-92a-1 cluster host gene)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51573/mir17hg-(mir-17-92a-1-cluster-host-gene)