LILRB1 (leukocyte immunoglobulin like receptor B1)

2010-08-01  

Identity

HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
CD85J,ILT-2,ILT2,LIR-1,LIR1,MIR-7,MIR7,PIR-B,PIRB
FUSION GENES

Other Information

Locus ID:

NCBI: 10859
MIM: 604811
HGNC: 6605
Ensembl: ENSG00000104972

Variants:

dbSNP: 10859
ClinVar: 10859
TCGA: ENSG00000104972
COSMIC: LILRB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104972ENST00000324602A0A087WSV6
ENSG00000104972ENST00000396315A0A087WSV6
ENSG00000104972ENST00000396317A8MVE2
ENSG00000104972ENST00000396327A0A087WSX8
ENSG00000104972ENST00000396331A0A0B4J1W1
ENSG00000104972ENST00000396332D9IDM5
ENSG00000104972ENST00000421584F6RVM3
ENSG00000104972ENST00000427581F6TER3

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Osteoclast differentiationKEGGko04380
Osteoclast differentiationKEGGhsa04380
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

References

Pubmed IDYearTitleCitations
383939692024ILT2 and ILT4 Drive Myeloid Suppression via Both Overlapping and Distinct Mechanisms.0
383939692024ILT2 and ILT4 Drive Myeloid Suppression via Both Overlapping and Distinct Mechanisms.0
368122902023TET2 and LILRB1 mutations are frequent in Epstein-Barr virus-positive diffuse large B-cell lymphoma especially in elderly patients.2
368312972023Evidence for Epistatic Interaction between HLA-G and LILRB1 in the Pathogenesis of Nonsegmental Vitiligo.1
369254352023Peripheral HLA-G/ILT-2 immune checkpoint axis in acute and convalescent COVID-19 patients.0
370792402023EIF4A3-induced circular RNA SCAP facilitates tumorigenesis and progression of non-small-cell lung cancer via miR-7/SMAD2 signaling.4
371429672023Elevated LILRB1 expression predicts poor prognosis and is associated with tumor immune infiltration in patients with glioma.3
376863972023HLA-F and LILRB1 Genetic Polymorphisms Associated with Alloimmunisation in Sickle Cell Disease.0
368122902023TET2 and LILRB1 mutations are frequent in Epstein-Barr virus-positive diffuse large B-cell lymphoma especially in elderly patients.2
368312972023Evidence for Epistatic Interaction between HLA-G and LILRB1 in the Pathogenesis of Nonsegmental Vitiligo.1
369254352023Peripheral HLA-G/ILT-2 immune checkpoint axis in acute and convalescent COVID-19 patients.0
370792402023EIF4A3-induced circular RNA SCAP facilitates tumorigenesis and progression of non-small-cell lung cancer via miR-7/SMAD2 signaling.4
371429672023Elevated LILRB1 expression predicts poor prognosis and is associated with tumor immune infiltration in patients with glioma.3
376863972023HLA-F and LILRB1 Genetic Polymorphisms Associated with Alloimmunisation in Sickle Cell Disease.0
350410512022HLA-G-ILT2 interaction contributes to suppression of bone marrow B cell proliferation in acquired aplastic anemia.1

Citation

Dessen P

LILRB1 (leukocyte immunoglobulin like receptor B1)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51630/lilrb1-(leukocyte-immunoglobulin-like-receptor-b1)