Identity
HGNC
LOCATION
12p13.1
LOCUSID
ALIAS
AM,ATF-IP,MCAF,MCAF1,p621
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55729
MIM: 613644
HGNC: 20092
Ensembl: ENSG00000171681
Variants:
dbSNP: 55729
ClinVar: 55729
TCGA: ENSG00000171681
COSMIC: ATF7IP
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| PKMTs methylate histone lysines | REACTOME | R-HSA-3214841 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35175239 | 2022 | Mutational Alterations of DNA Methylation-related Genes CTCF, ZFP57, and ATF7IP Genes in Colon Cancers. | 0 |
| 35175239 | 2022 | Mutational Alterations of DNA Methylation-related Genes CTCF, ZFP57, and ATF7IP Genes in Colon Cancers. | 0 |
| 31576654 | 2019 | ATF7IP regulates SETDB1 nuclear localization and increases its ubiquitination. | 37 |
| 31576654 | 2019 | ATF7IP regulates SETDB1 nuclear localization and increases its ubiquitination. | 37 |
| 30452683 | 2018 | Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations. | 16 |
| 30452683 | 2018 | Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations. | 16 |
| 29133777 | 2017 | Acute Lymphoblastic Leukemia Patient with Variant ATF7IP/PDGFRB Fusion and Favorable Response to Tyrosine Kinase Inhibitor Treatment: A Case Report. | 7 |
| 29133777 | 2017 | Acute Lymphoblastic Leukemia Patient with Variant ATF7IP/PDGFRB Fusion and Favorable Response to Tyrosine Kinase Inhibitor Treatment: A Case Report. | 7 |
| 26813693 | 2016 | Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IP. | 10 |
| 27732843 | 2016 | ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex. | 75 |
| 26813693 | 2016 | Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IP. | 10 |
| 27732843 | 2016 | ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex. | 75 |
| 24464130 | 2014 | The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance. | 43 |
| 24598729 | 2014 | MCAF1 and Rta-activated BZLF1 transcription in Epstein-Barr virus. | 5 |
| 24464130 | 2014 | The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance. | 43 |
Citation
Dessen P
ATF7IP (activating transcription factor 7 interacting protein)
Atlas Genet Cytogenet Oncol Haematol. 2010-08-01
Online version: http://atlasgeneticsoncology.org/gene/51647/atf7ip-(activating-transcription-factor-7-interacting-protein)
