Identity
HGNC
LOCATION
11q22.3
LOCUSID
ALIAS
GC-SA2,GUC1A2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2977
MIM: 601244
HGNC: 4684
Ensembl: ENSG00000152402
Variants:
dbSNP: 2977
ClinVar: 2977
TCGA: ENSG00000152402
COSMIC: GUCY1A2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000152402 | ENST00000282249 | P33402 |
| ENSG00000152402 | ENST00000347596 | P33402 |
| ENSG00000152402 | ENST00000526355 | P33402 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37667322 | 2023 | Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling. | 4 |
| 37667322 | 2023 | Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling. | 4 |
| 24669844 | 2014 | Interfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity. | 23 |
| 24669844 | 2014 | Interfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity. | 23 |
| 22426988 | 2012 | Structural and functional insights into the heme-binding domain of the human soluble guanylate cyclase α2 subunit and heterodimeric α2β1. | 0 |
| 22426988 | 2012 | Structural and functional insights into the heme-binding domain of the human soluble guanylate cyclase α2 subunit and heterodimeric α2β1. | 0 |
| 20978832 | 2011 | Gene-environment interaction in the etiology of mathematical ability using SNP sets. | 8 |
| 20978832 | 2011 | Gene-environment interaction in the etiology of mathematical ability using SNP sets. | 8 |
| 19948239 | 2010 | Role of soluble guanylyl cyclase-cyclic GMP signaling in tumor cell proliferation. | 27 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19948239 | 2010 | Role of soluble guanylyl cyclase-cyclic GMP signaling in tumor cell proliferation. | 27 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19240061 | 2009 | Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. | 94 |
| 19240061 | 2009 | Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. | 94 |
| 15094474 | 2004 | Expression of nNOS and soluble guanylate cyclase in schizophrenic brain. | 14 |
Citation
Dessen P
GUCY1A2 (guanylate cyclase 1 soluble subunit alpha 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-09-01
Online version: http://atlasgeneticsoncology.org/gene/51668/gucy1a2-(guanylate-cyclase-1-soluble-subunit-alpha-2)
