Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9914
MIM: 613082
HGNC: 29103
Ensembl: ENSG00000064270
Variants:
dbSNP: 9914
ClinVar: 9914
TCGA: ENSG00000064270
COSMIC: ATP2C2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000064270 | ENST00000262429 | O75185 |
| ENSG00000064270 | ENST00000416219 | O75185 |
| ENSG00000064270 | ENST00000569207 | H3BS90 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Transmembrane transport of small molecules | REACTOME | R-HSA-382551 |
| Ion channel transport | REACTOME | R-HSA-983712 |
| Ion transport by P-type ATPases | REACTOME | R-HSA-936837 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35063802 | 2022 | Secretory pathway Ca(2+)-ATPase SPCA2 regulates mitochondrial respiration and DNA damage response through store-independent calcium entry. | 4 |
| 35063802 | 2022 | Secretory pathway Ca(2+)-ATPase SPCA2 regulates mitochondrial respiration and DNA damage response through store-independent calcium entry. | 4 |
| 33864365 | 2021 | A rare missense variant in the ATP2C2 gene is associated with language impairment and related measures. | 9 |
| 33936088 | 2021 | ATP2C2 Has Potential to Define Tumor Microenvironment in Breast Cancer. | 10 |
| 33864365 | 2021 | A rare missense variant in the ATP2C2 gene is associated with language impairment and related measures. | 9 |
| 33936088 | 2021 | ATP2C2 Has Potential to Define Tumor Microenvironment in Breast Cancer. | 10 |
| 31676354 | 2020 | The pancreas-specific form of secretory pathway calcium ATPase 2 regulates multiple pathways involved in calcium homeostasis. | 5 |
| 31676354 | 2020 | The pancreas-specific form of secretory pathway calcium ATPase 2 regulates multiple pathways involved in calcium homeostasis. | 5 |
| 30718673 | 2019 | Original association of ion transporters mediates the ECM-induced breast cancer cell survival: Kv10.1-Orai1-SPCA2 partnership. | 20 |
| 31076498 | 2019 | A Ca(2+)-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells. | 21 |
| 30718673 | 2019 | Original association of ion transporters mediates the ECM-induced breast cancer cell survival: Kv10.1-Orai1-SPCA2 partnership. | 20 |
| 31076498 | 2019 | A Ca(2+)-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells. | 21 |
| 30003630 | 2018 | Genome-wide association meta-analysis of age at first cannabis use. | 19 |
| 30003630 | 2018 | Genome-wide association meta-analysis of age at first cannabis use. | 19 |
| 27692665 | 2017 | SPCA2 couples Ca(2+) influx via Orai1 to Ca(2+) uptake into the Golgi/secretory pathway. | 19 |
Citation
Dessen P
ATP2C2 (ATPase secretory pathway Ca2+ transporting 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-10-01
Online version: http://atlasgeneticsoncology.org/gene/51703/atp2c2-(atpase-secretory-pathway-ca2+-transporting-2)
