PLTP (phospholipid transfer protein)

2010-11-01  

Identity

HGNC
LOCATION
20q13.12
LOCUSID
ALIAS
BPIFE,HDLCQ9

Other Information

Locus ID:

NCBI: 5360
MIM: 172425
HGNC: 9093
Ensembl: ENSG00000100979

Variants:

dbSNP: 5360
ClinVar: 5360
TCGA: ENSG00000100979
COSMIC: PLTP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100979ENST00000354050P55058
ENSG00000100979ENST00000372420P55058
ENSG00000100979ENST00000372431P55058
ENSG00000100979ENST00000420868P55058
ENSG00000100979ENST00000477313P55058

Expression (GTEx)

0
50
100
150
200
250
300

Pathways

PathwaySourceExternal ID
PPAR signaling pathwayKEGGko03320
PPAR signaling pathwayKEGGhsa03320
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Lipoprotein metabolismREACTOMER-HSA-174824
HDL-mediated lipid transportREACTOMER-HSA-194223

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA24887APOA4GenePathwayassociated
PA49APOA1GenePathwayassociated

References

Pubmed IDYearTitleCitations
353412742022AGTR1, PLTP, and SCG2 associated with immune genes and immune cell infiltration in calcific aortic valve stenosis: analysis from integrated bioinformatics and machine learning.0
363090862022PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis.13
365441452022Exhaled phospholipid transfer protein and hepatocyte growth factor receptor in lung adenocarcinoma.3
353412742022AGTR1, PLTP, and SCG2 associated with immune genes and immune cell infiltration in calcific aortic valve stenosis: analysis from integrated bioinformatics and machine learning.0
363090862022PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis.13
365441452022Exhaled phospholipid transfer protein and hepatocyte growth factor receptor in lung adenocarcinoma.3
336316712021Lipocalin-1 is the acceptor protein for phospholipid transfer protein in tears.3
343858882021Association between the PLTP rs4810479 SNP and Serum Lipid Traits in the Chinese Maonan and Han Populations.0
336316712021Lipocalin-1 is the acceptor protein for phospholipid transfer protein in tears.3
343858882021Association between the PLTP rs4810479 SNP and Serum Lipid Traits in the Chinese Maonan and Han Populations.0
327357282020Identification of three predictors of gastric cancer progression and prognosis.9
327357282020Identification of three predictors of gastric cancer progression and prognosis.9
310178092019Identification of Novel Phospholipid Transfer Protein Inhibitors by High-Throughput Screening.0
310178092019Identification of Novel Phospholipid Transfer Protein Inhibitors by High-Throughput Screening.0
294389862018Phospholipid transfer protein: its impact on lipoprotein homeostasis and atherosclerosis.13

Citation

Dessen P

PLTP (phospholipid transfer protein)

Atlas Genet Cytogenet Oncol Haematol. 2010-11-01

Online version: http://atlasgeneticsoncology.org/gene/51749/pltp-(phospholipid-transfer-protein)