Identity
HGNC
LOCATION
9q34.2
LOCUSID
ALIAS
ADAMTSL-2,GPHYSD1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9719
MIM: 612277
HGNC: 14631
Ensembl: ENSG00000197859
Variants:
dbSNP: 9719
ClinVar: 9719
TCGA: ENSG00000197859
COSMIC: ADAMTSL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000197859 | ENST00000354484 | Q86TH1 |
| ENSG00000197859 | ENST00000393060 | Q86TH1 |
| ENSG00000197859 | ENST00000393061 | B1B0D4 |
| ENSG00000197859 | ENST00000651351 | Q86TH1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36896612 | 2023 | Al-Gazali Skeletal Dysplasia Constitutes the Lethal End of ADAMTSL2-Related Disorders. | 4 |
| 37187448 | 2023 | Secreted ADAMTS-like 2 promotes myoblast differentiation by potentiating WNT signaling. | 2 |
| 36896612 | 2023 | Al-Gazali Skeletal Dysplasia Constitutes the Lethal End of ADAMTSL2-Related Disorders. | 4 |
| 37187448 | 2023 | Secreted ADAMTS-like 2 promotes myoblast differentiation by potentiating WNT signaling. | 2 |
| 34600973 | 2022 | ADAMTSL2 protein and a soluble biomarker signature identify at-risk non-alcoholic steatohepatitis and fibrosis in adults with NAFLD. | 17 |
| 34936547 | 2022 | The relationship of ADAMTSL2 and LRPAP1 gene methylation level with rheumatoid arthritis activity. | 1 |
| 34958866 | 2022 | Aberrant interaction between mutated ADAMTSL2 and LTBP4 is associated with adolescent idiopathic scoliosis. | 3 |
| 34600973 | 2022 | ADAMTSL2 protein and a soluble biomarker signature identify at-risk non-alcoholic steatohepatitis and fibrosis in adults with NAFLD. | 17 |
| 34936547 | 2022 | The relationship of ADAMTSL2 and LRPAP1 gene methylation level with rheumatoid arthritis activity. | 1 |
| 34958866 | 2022 | Aberrant interaction between mutated ADAMTSL2 and LTBP4 is associated with adolescent idiopathic scoliosis. | 3 |
| 33369194 | 2021 | ADAMTSL2 gene variant in patients with features of autosomal dominant connective tissue disorders. | 5 |
| 34611183 | 2021 | The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts. | 14 |
| 33369194 | 2021 | ADAMTSL2 gene variant in patients with features of autosomal dominant connective tissue disorders. | 5 |
| 34611183 | 2021 | The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts. | 14 |
| 29758265 | 2019 | Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families. | 11 |
Citation
Dessen P
ADAMTSL2 (ADAMTS like 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-11-01
Online version: http://atlasgeneticsoncology.org/gene/51754/adamtsl2-(adamts-like-2)
