AKNA (AT-hook transcription factor)

2010-11-01  

Identity

HGNC
AKNA
LOCATION
9q32
LOCUSID
80709
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80709
MIM: 605729
HGNC: 24108
Ensembl: ENSG00000106948

Variants:

dbSNP: 80709
ClinVar: 80709
TCGA: ENSG00000106948
COSMIC: AKNA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106948ENST00000223791Q7Z591
ENSG00000106948ENST00000307564Q7Z591
ENSG00000106948ENST00000312033Q7Z591
ENSG00000106948ENST00000374075Q7Z591
ENSG00000106948ENST00000374079Q7Z591
ENSG00000106948ENST00000374088Q7Z591

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
212979672011Label-free proteomics reveals decreased expression of CD18 and AKNA in peripheral CD4+ T cells from patients with Vogt-Koyanagi-Harada syndrome.9
307874422019The centrosome protein AKNA regulates neurogenesis via microtubule organization.6
205072602010A polymorphism in the AT-hook motif of the transcriptional regulator AKNA is a risk factor for cervical cancer.5
205072602010A polymorphism in the AT-hook motif of the transcriptional regulator AKNA is a risk factor for cervical cancer.5
158694102005The human AKNA gene expresses multiple transcripts and protein isoforms as a result of alternative promoter usage, splicing, and polyadenylation.4
253737262015Cervical cancer-associated promoter polymorphism affects akna expression levels.3
293682742018The association of AKNA gene polymorphisms with knee osteoarthritis suggests the relevance of this immune response regulator in the disease genetic susceptibility.2
296186202018Orthoxenografts of Testicular Germ Cell Tumors Demonstrate Genomic Changes Associated with Cisplatin Resistance and Identify PDMP as a Resensitizing Agent.1

Citation

Dessen P

AKNA (AT-hook transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2010-11-01

Online version: http://atlasgeneticsoncology.org/gene/51764/akna-(at-hook-transcription-factor)