Identity
HGNC
LOCATION
5p13.3
LOCUSID
ALIAS
ETOHI2,HSA242976,RANSE3L,RN3,RNASE3L,RNASEN
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29102
MIM: 608828
HGNC: 17904
Ensembl: ENSG00000113360
Variants:
dbSNP: 29102
ClinVar: 29102
TCGA: ENSG00000113360
COSMIC: DROSHA
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA446155 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Disease | ClinicalAnnotation | associated | PD | 24614921 | |
| PA449165 | cyclophosphamide | Chemical | ClinicalAnnotation | associated | PD | 24614921 | |
| PA449177 | cytarabine | Chemical | ClinicalAnnotation | associated | PD | 24614921 | |
| PA449212 | daunorubicin | Chemical | ClinicalAnnotation | associated | PD | 24614921 | |
| PA450379 | mercaptopurine | Chemical | ClinicalAnnotation | associated | PD | 24614921 | |
| PA450428 | methotrexate | Chemical | ClinicalAnnotation | associated | PD | 24614921 | |
| PA451100 | prednisone | Chemical | ClinicalAnnotation | associated | PD | 24614921 | |
| PA451879 | vincristine | Chemical | ClinicalAnnotation | associated | PD | 24614921 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38241848 | 2024 | Cytoplasmic and nuclear DROSHA in human villous trophoblasts. | 0 |
| 38241848 | 2024 | Cytoplasmic and nuclear DROSHA in human villous trophoblasts. | 0 |
| 36911928 | 2023 | Association of DROSHA rs6877842, rs642321 and rs10719 polymorphisms with increased susceptibility to breast cancer: A case-control study with genotype and haplotype analysis. | 0 |
| 36983035 | 2023 | Downregulation of DROSHA: Could It Affect miRNA Biogenesis in Endometriotic Menstrual Blood Mesenchymal Stem Cells? | 1 |
| 37099569 | 2023 | The 3' UTR polymorphisms rs3742330 in DICER1 and rs10719 in DROSHA genes are not associated with primary open-angle and angle-closure glaucoma: As case-control study. | 0 |
| 36911928 | 2023 | Association of DROSHA rs6877842, rs642321 and rs10719 polymorphisms with increased susceptibility to breast cancer: A case-control study with genotype and haplotype analysis. | 0 |
| 36983035 | 2023 | Downregulation of DROSHA: Could It Affect miRNA Biogenesis in Endometriotic Menstrual Blood Mesenchymal Stem Cells? | 1 |
| 37099569 | 2023 | The 3' UTR polymorphisms rs3742330 in DICER1 and rs10719 in DROSHA genes are not associated with primary open-angle and angle-closure glaucoma: As case-control study. | 0 |
| 34855193 | 2022 | The impact of Dicer, Drosha, and Exportin-5 levels in polycystic ovary syndrome (PCOS) diagnosis and phenotyping. | 0 |
| 35405010 | 2022 | The microRNA processor DROSHA is a candidate gene for a severe progressive neurological disorder. | 1 |
| 36210981 | 2022 | The Drosha-Independent MicroRNA6778-5p/GSK3β Axis Mediates the Proliferation of Gastric Cancer Cells. | 0 |
| 36515351 | 2022 | Immunohistochemical expression of Drosha is reduced in eutopic and ectopic endometrium of women with adenomyosis. | 1 |
| 34855193 | 2022 | The impact of Dicer, Drosha, and Exportin-5 levels in polycystic ovary syndrome (PCOS) diagnosis and phenotyping. | 0 |
| 35405010 | 2022 | The microRNA processor DROSHA is a candidate gene for a severe progressive neurological disorder. | 1 |
| 36210981 | 2022 | The Drosha-Independent MicroRNA6778-5p/GSK3β Axis Mediates the Proliferation of Gastric Cancer Cells. | 0 |
Citation
Dessen P
DROSHA (drosha ribonuclease III)
Atlas Genet Cytogenet Oncol Haematol. 2010-11-01
Online version: http://atlasgeneticsoncology.org/gene/51768
