Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57521
MIM: 607130
HGNC: 30287
Ensembl: ENSG00000141564
Variants:
dbSNP: 57521
ClinVar: 57521
TCGA: ENSG00000141564
COSMIC: RPTOR
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164746311 | everolimus | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | ||
| PA166123026 | progression-free survival | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | ||
| PA166124223 | pneumonitis | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | ||
| PA443560 | Breast Neoplasms | Disease | VariantAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38010109 | 2024 | MALAT1 DEREPRESSES MIR-433-3P-MEDIATED RPTOR SUPPRESSION TO IMPAIR AUTOPHAGY AND DRIVE PYROPTOSIS IN ENDOTOXEMIA. | 0 |
| 38497230 | 2024 | Role of Raptor Gene Variants in Hypertension: Influence on Blood Pressure Independent of Salt Intake in White Population. | 0 |
| 38010109 | 2024 | MALAT1 DEREPRESSES MIR-433-3P-MEDIATED RPTOR SUPPRESSION TO IMPAIR AUTOPHAGY AND DRIVE PYROPTOSIS IN ENDOTOXEMIA. | 0 |
| 38497230 | 2024 | Role of Raptor Gene Variants in Hypertension: Influence on Blood Pressure Independent of Salt Intake in White Population. | 0 |
| 36192581 | 2023 | RBM3 interacts with Raptor to regulate autophagy and protect cardiomyocytes from ischemia-reperfusion-induced injury. | 3 |
| 37493735 | 2023 | Association of PI3K/AKT/mTOR pathway autophagy-related gene polymorphisms with pulmonary tuberculosis susceptibility in a Chinese population. | 0 |
| 37749558 | 2023 | Raptor mediates the selective inhibitory effect of cardamonin on RRAGC-mutant B cell lymphoma. | 0 |
| 36192581 | 2023 | RBM3 interacts with Raptor to regulate autophagy and protect cardiomyocytes from ischemia-reperfusion-induced injury. | 3 |
| 37493735 | 2023 | Association of PI3K/AKT/mTOR pathway autophagy-related gene polymorphisms with pulmonary tuberculosis susceptibility in a Chinese population. | 0 |
| 37749558 | 2023 | Raptor mediates the selective inhibitory effect of cardamonin on RRAGC-mutant B cell lymphoma. | 0 |
| 34767153 | 2022 | RPTOR methylation in the peripheral blood and breast cancer in the Chinese population. | 3 |
| 34767153 | 2022 | RPTOR methylation in the peripheral blood and breast cancer in the Chinese population. | 3 |
| 32576051 | 2021 | The Association between the Plasma Sugar and Lipid Profile with the Gene Expression of the Regulatory Protein of mTOR (Raptor) in Patients with Rheumatoid Arthritis. | 2 |
| 33482765 | 2021 | Raptor and rictor expression in patients with human papillomavirus-related oropharyngeal squamous cell carcinoma. | 9 |
| 33852892 | 2021 | The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1. | 20 |
Citation
Dessen P
RPTOR (regulatory associated protein of MTOR complex 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-12-01
Online version: http://atlasgeneticsoncology.org/gene/51833/rptor-(regulatory-associated-protein-of-mtor-complex-1)
