BECN2 (beclin 2)

2010-12-01  

Identity

HGNC
LOCATION
1q43
LOCUSID
ALIAS
BECN1L1,BECN1P1

Other Information

Locus ID:

NCBI: 441925
MIM: 615687
HGNC: 38606
Ensembl: ENSG00000196289

Variants:

dbSNP: 441925
ClinVar: 441925
TCGA: ENSG00000196289
COSMIC: BECN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196289ENST00000419583A8MW95

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
Apoptosis - multiple speciesKEGGko04215
Apoptosis - multiple speciesKEGGhsa04215
Apelin signaling pathwayKEGGhsa04371
Mitophagy - animalKEGGko04137
Mitophagy - animalKEGGhsa04137
Autophagy - otherKEGGko04136
Autophagy - otherKEGGhsa04136

References

Pubmed IDYearTitleCitations
328655192020Beclin 2 negatively regulates innate immune signaling and tumor development.15
328655192020Beclin 2 negatively regulates innate immune signaling and tumor development.15
282184322017BECN2 interacts with ATG14 through a metastable coiled-coil to mediate autophagy.6
285153042017Reactive Oxygen Species-Mediated c-Jun NH(2)-Terminal Kinase Activation Contributes to Hepatitis B Virus X Protein-Induced Autophagy via Regulation of the Beclin-1/Bcl-2 Interaction.38
282184322017BECN2 interacts with ATG14 through a metastable coiled-coil to mediate autophagy.6
285153042017Reactive Oxygen Species-Mediated c-Jun NH(2)-Terminal Kinase Activation Contributes to Hepatitis B Virus X Protein-Induced Autophagy via Regulation of the Beclin-1/Bcl-2 Interaction.38
269293732016Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis.12
269293732016Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis.12
265061052015Expression of Beclin Family Proteins Is Associated with Tumor Progression in Oral Cancer.12
265061052015Expression of Beclin Family Proteins Is Associated with Tumor Progression in Oral Cancer.12
239544142013Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism.79
239544142013Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism.79

Citation

Dessen P

BECN2 (beclin 2)

Atlas Genet Cytogenet Oncol Haematol. 2010-12-01

Online version: http://atlasgeneticsoncology.org/gene/51838/becn2-(beclin-2)