BECN2 (beclin 2)

2010-12-01  

Identity

HGNC
LOCATION
1q43
LOCUSID
ALIAS
BECN1L1,BECN1P1

Other Information

Locus ID:

NCBI: 441925
MIM: 615687
HGNC: 38606
Ensembl: ENSG00000196289

Variants:

dbSNP: 441925
ClinVar: 441925
TCGA: ENSG00000196289
COSMIC: BECN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196289ENST00000419583A8MW95

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
Apoptosis - multiple speciesKEGGko04215
Apoptosis - multiple speciesKEGGhsa04215
Apelin signaling pathwayKEGGhsa04371
Mitophagy - animalKEGGko04137
Mitophagy - animalKEGGhsa04137
Autophagy - otherKEGGko04136
Autophagy - otherKEGGhsa04136

References

Pubmed IDYearTitleCitations
285153042017Reactive Oxygen Species-Mediated c-Jun NH2-Terminal Kinase Activation Contributes to Hepatitis B Virus X Protein-Induced Autophagy via Regulation of the Beclin-1/Bcl-2 Interaction.25
265061052015Expression of Beclin Family Proteins Is Associated with Tumor Progression in Oral Cancer.7
269293732016Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis.6
282184322017BECN2 interacts with ATG14 through a metastable coiled-coil to mediate autophagy.4
239544142013Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism.0

Citation

Dessen P

BECN2 (beclin 2)

Atlas Genet Cytogenet Oncol Haematol. 2010-12-01

Online version: http://atlasgeneticsoncology.org/gene/51838/becn2-(beclin-2)