Identity
HGNC
LOCATION
6p21.33
LOCUSID
ALIAS
BAG-6,BAT3,D6S52E,G3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7917
MIM: 142590
HGNC: 13919
Ensembl: ENSG00000204463
Variants:
dbSNP: 7917
ClinVar: 7917
TCGA: ENSG00000204463
COSMIC: BAG6
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA448785 | carbamazepine | Chemical | ClinicalAnnotation | associated | PD | 16538176 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37815698 | 2024 | DERL2 (derlin 2) stabilizes BAG6 (BAG cochaperone 6) in chemotherapy resistance of cholangiocarcinoma. | 0 |
| 37815698 | 2024 | DERL2 (derlin 2) stabilizes BAG6 (BAG cochaperone 6) in chemotherapy resistance of cholangiocarcinoma. | 0 |
| 34704338 | 2022 | GET4 is a novel driver gene in colorectal cancer that regulates the localization of BAG6, a nucleocytoplasmic shuttling protein. | 5 |
| 35543156 | 2022 | Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex. | 1 |
| 34704338 | 2022 | GET4 is a novel driver gene in colorectal cancer that regulates the localization of BAG6, a nucleocytoplasmic shuttling protein. | 5 |
| 35543156 | 2022 | Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex. | 1 |
| 33522017 | 2021 | BAG6 promotes PINK1 signaling pathway and is essential for mitophagy. | 10 |
| 33539267 | 2021 | Association Between eNOS, MMP-9, BAG-6 Gene Polymorphisms and Risk of Hypertensive Disorders of Pregnancy in the Northern Chinese Population. | 1 |
| 33671836 | 2021 | Secreted Ligands of the NK Cell Receptor NKp30: B7-H6 Is in Contrast to BAG6 Only Marginally Released via Extracellular Vesicles. | 7 |
| 33522017 | 2021 | BAG6 promotes PINK1 signaling pathway and is essential for mitophagy. | 10 |
| 33539267 | 2021 | Association Between eNOS, MMP-9, BAG-6 Gene Polymorphisms and Risk of Hypertensive Disorders of Pregnancy in the Northern Chinese Population. | 1 |
| 33671836 | 2021 | Secreted Ligands of the NK Cell Receptor NKp30: B7-H6 Is in Contrast to BAG6 Only Marginally Released via Extracellular Vesicles. | 7 |
| 31647545 | 2020 | HLA-B-associated transcript 3 (Bat3) stabilizes and activates p53 in a HAUSP-dependent manner. | 2 |
| 31838060 | 2020 | BAG6 is a novel microtubule-binding protein that regulates ciliogenesis by modulating the cell cycle and interacting with γ-tubulin. | 3 |
| 31904842 | 2020 | PAQR9 Modulates BAG6-mediated protein quality control of mislocalized membrane proteins. | 2 |
Citation
Dessen P
BAG6 (BAG cochaperone 6)
Atlas Genet Cytogenet Oncol Haematol. 2010-12-01
Online version: http://atlasgeneticsoncology.org/gene/51841/bag6-(bag-cochaperone-6)
