Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55666
MIM: 606590
HGNC: 18261
Ensembl: ENSG00000182446
Variants:
dbSNP: 55666
ClinVar: 55666
TCGA: ENSG00000182446
COSMIC: NPLOC4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37993584 | 2023 | NPLOC4 is a potential target and a poor prognostic signature in lung squamous cell carcinoma. | 1 |
| 37993584 | 2023 | NPLOC4 is a potential target and a poor prognostic signature in lung squamous cell carcinoma. | 1 |
| 35920641 | 2022 | Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase. | 11 |
| 36087575 | 2022 | Structural basis for the interaction between human Npl4 and Npl4-binding motif of human Ufd1. | 2 |
| 35920641 | 2022 | Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase. | 11 |
| 36087575 | 2022 | Structural basis for the interaction between human Npl4 and Npl4-binding motif of human Ufd1. | 2 |
| 33402676 | 2021 | Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative. | 35 |
| 33402676 | 2021 | Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative. | 35 |
| 32667929 | 2020 | Targeting NPL4 via drug repositioning using disulfiram for the treatment of clear cell renal cell carcinoma. | 11 |
| 32667929 | 2020 | Targeting NPL4 via drug repositioning using disulfiram for the treatment of clear cell renal cell carcinoma. | 11 |
| 31623962 | 2019 | Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing. | 40 |
| 31623962 | 2019 | Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing. | 40 |
| 28512218 | 2017 | Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy. | 96 |
| 28512218 | 2017 | Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy. | 96 |
| 26112410 | 2015 | The Transitional Endoplasmic Reticulum ATPase p97 Regulates the Alternative Nuclear Factor NF-κB Signaling via Partial Degradation of the NF-κB Subunit p100. | 13 |
Citation
Dessen P
NPLOC4 (NPL4 homolog, ubiquitin recognition factor)
Atlas Genet Cytogenet Oncol Haematol. 2011-01-01
Online version: http://atlasgeneticsoncology.org/gene/51979/nploc4-(npl4-homolog-ubiquitin-recognition-factor)
