BAZ1A (bromodomain adjacent to zinc finger domain 1A)

2011-02-01  

Identity

HGNC
BAZ1A
LOCATION
14q13.1
LOCUSID
11177
ALIAS
ACF1,WALp1,WCRF180,hACF1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11177
MIM: 605680
HGNC: 960
Ensembl: ENSG00000198604

Variants:

dbSNP: 11177
ClinVar: 11177
TCGA: ENSG00000198604
COSMIC: BAZ1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198604ENST00000358716Q9NRL2
ENSG00000198604ENST00000360310Q9NRL2
ENSG00000198604ENST00000382422Q9NRL2
ENSG00000198604ENST00000553573H0YJP5
ENSG00000198604ENST00000554865H0YJ74
ENSG00000198604ENST00000555331H0YJ68
ENSG00000198604ENST00000556314A0A087WWN7

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
211726622010The ACF1 complex is required for DNA double-strand break repair in human cells.91
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
255338432014Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair.37
168777602006Human ACF1 alters the remodeling strategy of SNF2h.32
217458222011Role for hACF1 in the G2/M damage checkpoint.31
194506082009Chromatin remodelers act globally, sequence positions nucleosomes locally.21
217388332011Binding kinetics of human ISWI chromatin-remodelers to DNA repair sites elucidate their target location mechanism.21
262882492015Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.17
175193542007Novel regulatory role for human Acf1 in transcriptional repression of vitamin D3 receptor-regulated genes.12
273288122016A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment.10

Citation

Dessen P

BAZ1A (bromodomain adjacent to zinc finger domain 1A)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52060/baz1a-(bromodomain-adjacent-to-zinc-finger-domain-1a)