MIR181A2 (microRNA 181a-2)

2011-02-01  

Identity

HGNC
LOCATION
9q33.3
LOCUSID
ALIAS
MIRN181A,MIRN181A2,hsa-mir-181a-2,mir-181a-2

Other Information

Locus ID:

NCBI: 406954
MIM: 612743
HGNC: 31549
Ensembl: ENSG00000207595
miRBase:

Variants:

dbSNP: 406954
ClinVar: 406954
TCGA: ENSG00000207595
COSMIC: MIR181A2

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
230235002012Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity.131
243945552014microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial-mesenchymal transition.85
220428112011Gene expression profiling reveals renin mRNA overexpression in human hypertensive kidneys and a role for microRNAs.72
192214872009MicroRNAs181 regulate the expression of p27Kip1 in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D3.61
233220782013MIR181A regulates starvation- and rapamycin-induced autophagy through targeting of ATG5.60
230857572013miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.57
228476112013MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD gene.35
208415062010Follicular dendritic cell-dependent drug resistance of non-Hodgkin lymphoma involves cell adhesion-mediated Bim down-regulation through induction of microRNA-181a.32
225815222012MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6.29
246856942014miR-181a mediates metabolic shift in colon cancer cells via the PTEN/AKT pathway.27

Citation

Dessen P

MIR181A2 (microRNA 181a-2)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52065/mir181a2-(microrna-181a-2)