Identity
HGNC
LOCATION
11q21
LOCUSID
ALIAS
MRS1,OOMD7,PX1,UNQ2529
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 24145
MIM: 608420
HGNC: 8599
Ensembl: ENSG00000110218
Variants:
dbSNP: 24145
ClinVar: 24145
TCGA: ENSG00000110218
COSMIC: PANX1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000110218 | ENST00000227638 | Q96RD7 |
| ENSG00000110218 | ENST00000227638 | A0A024R397 |
| ENSG00000110218 | ENST00000436171 | Q96RD7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38073055 | 2024 | Reduced Ca(2+) mobilization in neonatal human platelets involves SARAF and pannexin-1. | 0 |
| 38861601 | 2024 | Ca(2+) permeation through C-terminal cleaved, but not full-length human Pannexin1 hemichannels, mediates cell death. | 2 |
| 38897345 | 2024 | Pannexin-1 expression in tumor cells correlates with colon cancer progression and survival. | 0 |
| 38937853 | 2024 | PANX1-mediated ATP release confers FAM3A's suppression effects on hepatic gluconeogenesis and lipogenesis. | 0 |
| 38073055 | 2024 | Reduced Ca(2+) mobilization in neonatal human platelets involves SARAF and pannexin-1. | 0 |
| 38861601 | 2024 | Ca(2+) permeation through C-terminal cleaved, but not full-length human Pannexin1 hemichannels, mediates cell death. | 2 |
| 38897345 | 2024 | Pannexin-1 expression in tumor cells correlates with colon cancer progression and survival. | 0 |
| 38937853 | 2024 | PANX1-mediated ATP release confers FAM3A's suppression effects on hepatic gluconeogenesis and lipogenesis. | 0 |
| 36469255 | 2023 | A novel heterozygous variant in PANX1 causes primary infertility due to oocyte death. | 0 |
| 36610467 | 2023 | Increased serum pannexin-1 concentrations reflect illness severity and predict a poor prognosis after acute supratentorial intracerebral hemorrhage: A prospective longitudinal cohort study. | 2 |
| 37073958 | 2023 | Expression of pannexin1 in lung cancer brain metastasis and immune microenvironment. | 0 |
| 37130457 | 2023 | Carboxyl terminus of Pannexin-1 plays a crucial role in P2X7 receptor-mediated signaling. | 2 |
| 37511370 | 2023 | Cx43 Hemichannel and Panx1 Channel Modulation by Gap19 and (10)Panx1 Peptides. | 0 |
| 37589139 | 2023 | Pannexin 1 Modulates Angiogenic Activities of Human Endothelial Colony-Forming Cells Through IGF-1 Mechanism and Is a Marker of Senescence. | 2 |
| 37622532 | 2023 | Recent advances in the structure and activation mechanisms of metabolite-releasing Pannexin 1 channels. | 0 |
Citation
Dessen P
PANX1 (pannexin 1)
Atlas Genet Cytogenet Oncol Haematol. 2011-02-01
Online version: http://atlasgeneticsoncology.org/gene/52073/panx1-(pannexin-1)
