Identity
HGNC
LOCATION
7q11.23
LOCUSID
ALIAS
WBSCR1,WSCR1,eIF-4H
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7458
MIM: 603431
HGNC: 12741
Ensembl: ENSG00000106682
Variants:
dbSNP: 7458
ClinVar: 7458
TCGA: ENSG00000106682
COSMIC: EIF4H
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000106682 | ENST00000265753 | Q15056 |
| ENSG00000106682 | ENST00000353999 | Q15056 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33130397 | 2020 | RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H. | 24 |
| 33130397 | 2020 | RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H. | 24 |
| 31023341 | 2019 | eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS. | 32 |
| 31023341 | 2019 | eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS. | 32 |
| 28351305 | 2017 | Overexpression of miR-519d in lung adenocarcinoma inhibits cell proliferation and invasion via the association of eIF4H. | 9 |
| 28351305 | 2017 | Overexpression of miR-519d in lung adenocarcinoma inhibits cell proliferation and invasion via the association of eIF4H. | 9 |
| 26498689 | 2015 | Key contribution of eIF4H-mediated translational control in tumor promotion. | 17 |
| 26498689 | 2015 | Key contribution of eIF4H-mediated translational control in tumor promotion. | 17 |
| 23776612 | 2013 | Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF-κB. | 15 |
| 23776612 | 2013 | Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF-κB. | 15 |
| 20473909 | 2011 | An alternative splicing isoform of eukaryotic initiation factor 4H promotes tumorigenesis in vivo and is a potential therapeutic target for human cancer. | 11 |
| 21427765 | 2011 | mRNA helicases: the tacticians of translational control. | 187 |
| 20473909 | 2011 | An alternative splicing isoform of eukaryotic initiation factor 4H promotes tumorigenesis in vivo and is a potential therapeutic target for human cancer. | 11 |
| 21427765 | 2011 | mRNA helicases: the tacticians of translational control. | 187 |
| 19847924 | 2010 | Detecting rare variants for complex traits using family and unrelated data. | 84 |
Citation
Dessen P
EIF4H (eukaryotic translation initiation factor 4H)
Atlas Genet Cytogenet Oncol Haematol. 2011-02-01
Online version: http://atlasgeneticsoncology.org/gene/52093/eif4h-(eukaryotic-translation-initiation-factor-4h)
