Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5547
MIM: 176785
HGNC: 9344
Ensembl: ENSG00000137509
Variants:
dbSNP: 5547
ClinVar: 5547
TCGA: ENSG00000137509
COSMIC: PRCP
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | 20079160 | |
| PA448561 | benazepril | Chemical | ClinicalAnnotation | associated | PD | 20079160 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31837203 | 2020 | Fast oxidation of α-melanocyte-stimulating hormone and derived peptides under laboratory conditions causes irreproducible results-Insights from studies of prolylcarboxypeptidase in human cell types. | 1 |
| 32448049 | 2020 | Genetic association study of prolylcarboxypeptidase polymorphisms with susceptibility to essential hypertension in the Yi minority of China: A case-control study based on an isolated population. | 2 |
| 33319614 | 2020 | Haplotype-based association study between PRCP gene polymorphisms and essential hypertension in Hani minority group from a remote region of China. | 0 |
| 31837203 | 2020 | Fast oxidation of α-melanocyte-stimulating hormone and derived peptides under laboratory conditions causes irreproducible results-Insights from studies of prolylcarboxypeptidase in human cell types. | 1 |
| 32448049 | 2020 | Genetic association study of prolylcarboxypeptidase polymorphisms with susceptibility to essential hypertension in the Yi minority of China: A case-control study based on an isolated population. | 2 |
| 33319614 | 2020 | Haplotype-based association study between PRCP gene polymorphisms and essential hypertension in Hani minority group from a remote region of China. | 0 |
| 28831120 | 2017 | Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. | 8 |
| 28831120 | 2017 | Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. | 8 |
| 27449720 | 2016 | Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme. | 9 |
| 27449720 | 2016 | Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme. | 9 |
| 25370794 | 2015 | Prolyl carboxypeptidase activity decline correlates with severity and short-term outcome in acute ischemic stroke. | 5 |
| 25370794 | 2015 | Prolyl carboxypeptidase activity decline correlates with severity and short-term outcome in acute ischemic stroke. | 5 |
| 25324000 | 2014 | Prolylcarboxypeptidase independently activates plasma prekallikrein (fletcher factor). | 11 |
| 25324000 | 2014 | Prolylcarboxypeptidase independently activates plasma prekallikrein (fletcher factor). | 11 |
| 22679278 | 2013 | Association of polymorphisms in prolylcarboxypeptidase and chymase genes with essential hypertension in the Chinese Han population. | 9 |
Citation
Dessen P
PRCP (prolylcarboxypeptidase)
Atlas Genet Cytogenet Oncol Haematol. 2011-03-01
Online version: http://atlasgeneticsoncology.org/gene/52116/prcp-(prolylcarboxypeptidase)
