Identity
HGNC
LOCATION
11q13.4
LOCUSID
ALIAS
C11orf59,PDRO,Ragulator1,p18,p27RF-Rho
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55004
MIM: 613510
HGNC: 26068
Ensembl: ENSG00000149357
Variants:
dbSNP: 55004
ClinVar: 55004
TCGA: ENSG00000149357
COSMIC: LAMTOR1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38229144 | 2024 | TRAF4-Mediated LAMTOR1 Ubiquitination Promotes mTORC1 Activation and Inhibits the Inflammation-Induced Colorectal Cancer Progression. | 1 |
| 38229144 | 2024 | TRAF4-Mediated LAMTOR1 Ubiquitination Promotes mTORC1 Activation and Inhibits the Inflammation-Induced Colorectal Cancer Progression. | 1 |
| 34999170 | 2022 | N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression. | 10 |
| 36070764 | 2022 | LAMTOR1 degrades MHC-II via the endocytic in hepatocellular carcinoma. | 3 |
| 34999170 | 2022 | N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression. | 10 |
| 36070764 | 2022 | LAMTOR1 degrades MHC-II via the endocytic in hepatocellular carcinoma. | 3 |
| 30877085 | 2019 | Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel AKT1 Fusion-Driven Cancer. | 8 |
| 30877085 | 2019 | Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel AKT1 Fusion-Driven Cancer. | 8 |
| 29547888 | 2018 | The TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex. | 14 |
| 30806216 | 2018 | Roles of Lamtor1 in Macrophages, CD4+ T-cells, and Regulatory T-cells. | 1 |
| 29547888 | 2018 | The TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex. | 14 |
| 30806216 | 2018 | Roles of Lamtor1 in Macrophages, CD4+ T-cells, and Regulatory T-cells. | 1 |
| 27664330 | 2017 | Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation. | 43 |
| 28174230 | 2017 | Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9-coupled Affinity Purification/Mass Spectrometry Analysis Revealed a Novel Role of Neurofibromin in mTOR Signaling. | 9 |
| 28935770 | 2017 | Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling. | 71 |
Citation
Dessen P
LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1)
Atlas Genet Cytogenet Oncol Haematol. 2011-03-01
Online version: http://atlasgeneticsoncology.org/gene/52126
