EIF3M (eukaryotic translation initiation factor 3 subunit M)

2011-03-01  

Identity

HGNC
LOCATION
11p13
LOCUSID
ALIAS
B5,GA17,PCID1,TANGO7,hfl-B5
FUSION GENES

Other Information

Locus ID:

NCBI: 10480
MIM: 609641
HGNC: 24460
Ensembl: ENSG00000149100

Variants:

dbSNP: 10480
ClinVar: 10480
TCGA: ENSG00000149100
COSMIC: EIF3M

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149100ENST00000323213J3KNJ2
ENSG00000149100ENST00000524711E9PRI2
ENSG00000149100ENST00000524896Q7L2H7
ENSG00000149100ENST00000525782E9PRY0
ENSG00000149100ENST00000526267H0YCQ8
ENSG00000149100ENST00000531120Q7L2H7
ENSG00000149100ENST00000531921E7ESM3
ENSG00000149100ENST00000532444E9PSB3
ENSG00000149100ENST00000533439E9PN86

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
Eukaryotic Translation InitiationREACTOMER-HSA-72613
Cap-dependent Translation InitiationREACTOMER-HSA-72737
Formation of a pool of free 40S subunitsREACTOMER-HSA-72689
Formation of the ternary complex, and subsequently, the 43S complexREACTOMER-HSA-72695
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43SREACTOMER-HSA-72662
Translation initiation complex formationREACTOMER-HSA-72649
Ribosomal scanning and start codon recognitionREACTOMER-HSA-72702
GTP hydrolysis and joining of the 60S ribosomal subunitREACTOMER-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expressionREACTOMER-HSA-156827
Gene ExpressionREACTOMER-HSA-74160

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
194836762009Genome-wide silencing in Drosophila captures conserved apoptotic effectors.21
208383792011eIF3m expression influences the regulation of tumorigenesis-related genes in human colon cancer.18
159198982005A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins.15
159198992005The C terminus of the B5 receptor for herpes simplex virus contains a functional region important for infection.7
206764072010HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target.6
220229722011A minor isoform of the human RNA polymerase II subunit hRPB11 (POLR2J) interacts with several components of the translation initiation factor eIF3.2

Citation

Dessen P

EIF3M (eukaryotic translation initiation factor 3 subunit M)

Atlas Genet Cytogenet Oncol Haematol. 2011-03-01

Online version: http://atlasgeneticsoncology.org/gene/52139/eif3m-(eukaryotic-translation-initiation-factor-3-subunit-m)