RAMP3 (receptor activity modifying protein 3)

2011-03-01  

Identity

HGNC
RAMP3
LOCATION
7p13
LOCUSID
10268
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10268
MIM: 605155
HGNC: 9845
Ensembl: ENSG00000122679

Variants:

dbSNP: 10268
ClinVar: 10268
TCGA: ENSG00000122679
COSMIC: RAMP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122679ENST00000242249O60896
ENSG00000122679ENST00000242249A4D2L1
ENSG00000122679ENST00000481345O60896
ENSG00000122679ENST00000481345A4D2L1
ENSG00000122679ENST00000496212J3KR56

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vascular smooth muscle contractionKEGGhsa04270
Vascular smooth muscle contractionKEGGko04270
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Calcitonin-like ligand receptorsREACTOMER-HSA-419812
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555

References

Pubmed IDYearTitleCitations
337113142021Adrenomedullin 2 and 5 activate the calcitonin receptor-like receptor (clr) - Receptor activity-modifying protein 3 (ramp3) receptor complex in Xenopus tropicalis.1
337113142021Adrenomedullin 2 and 5 activate the calcitonin receptor-like receptor (clr) - Receptor activity-modifying protein 3 (ramp3) receptor complex in Xenopus tropicalis.1
298826792018RAMP3 is a prognostic indicator of liver cancer and might reduce the adverse effect of TP53 mutation on survival.10
298826792018RAMP3 is a prognostic indicator of liver cancer and might reduce the adverse effect of TP53 mutation on survival.10
270136572016Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties.25
270136572016Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties.25
241693182014Adrenomedullin expression in the developing human fetal lung.4
241996272014Receptor activity-modifying protein-dependent effects of mutations in the calcitonin receptor-like receptor: implications for adrenomedullin and calcitonin gene-related peptide pharmacology.20
248319422014Expression and distribution of the adrenomedullin system in newborn human thymus.7
241693182014Adrenomedullin expression in the developing human fetal lung.4
241996272014Receptor activity-modifying protein-dependent effects of mutations in the calcitonin receptor-like receptor: implications for adrenomedullin and calcitonin gene-related peptide pharmacology.20
248319422014Expression and distribution of the adrenomedullin system in newborn human thymus.7
224457532012Characterization of the single transmembrane domain of human receptor activity-modifying protein 3 in adrenomedullin receptor internalization.2
224457532012Characterization of the single transmembrane domain of human receptor activity-modifying protein 3 in adrenomedullin receptor internalization.2
208021052011Receptor activity modifying protein-3 mediates the protumorigenic activity of lysyl oxidase-like protein-2.21

Citation

Dessen P

RAMP3 (receptor activity modifying protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2011-03-01

Online version: http://atlasgeneticsoncology.org/gene/52142/ramp3-(receptor-activity-modifying-protein-3)