Identity
HGNC
LOCATION
2q36.3
LOCUSID
ALIAS
C2orf33,EMPF2,GL004
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56947
MIM: 614785
HGNC: 24858
Ensembl: ENSG00000168958
Variants:
dbSNP: 56947
ClinVar: 56947
TCGA: ENSG00000168958
COSMIC: MFF
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34750646 | 2022 | Mitochondrial "dysmorphology" in variant classification. | 0 |
| 34750646 | 2022 | Mitochondrial "dysmorphology" in variant classification. | 0 |
| 34347505 | 2021 | Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division. | 13 |
| 34460078 | 2021 | Hypoxia-induced ROS promotes mitochondrial fission and cisplatin chemosensitivity via HIF-1α/Mff regulation in head and neck squamous cell carcinoma. | 12 |
| 34347505 | 2021 | Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division. | 13 |
| 34460078 | 2021 | Hypoxia-induced ROS promotes mitochondrial fission and cisplatin chemosensitivity via HIF-1α/Mff regulation in head and neck squamous cell carcinoma. | 12 |
| 31941601 | 2020 | Mcl-1 inhibits Mff-mediated mitochondrial fragmentation and apoptosis. | 2 |
| 32181496 | 2020 | Encephalopathy due to defective mitochondrial and peroxisomal fission 2 caused by a novel MFF gene mutation in a young child. | 12 |
| 32224193 | 2020 | Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation. | 15 |
| 31941601 | 2020 | Mcl-1 inhibits Mff-mediated mitochondrial fragmentation and apoptosis. | 2 |
| 32181496 | 2020 | Encephalopathy due to defective mitochondrial and peroxisomal fission 2 caused by a novel MFF gene mutation in a young child. | 12 |
| 32224193 | 2020 | Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation. | 15 |
| 30191967 | 2019 | DUSP1 recuses diabetic nephropathy via repressing JNK-Mff-mitochondrial fission pathways. | 42 |
| 31533986 | 2019 | The phosphorylation status of Ser-637 in dynamin-related protein 1 (Drp1) does not determine Drp1 recruitment to mitochondria. | 45 |
| 31582380 | 2019 | MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer. | 27 |
Citation
Dessen P
MFF (mitochondrial fission factor)
Atlas Genet Cytogenet Oncol Haematol. 2011-04-01
Online version: http://atlasgeneticsoncology.org/gene/52156/mff-(mitochondrial-fission-factor)
