SGK3 (serum/glucocorticoid regulated kinase family member 3)

2011-04-01  

Identity

HGNC
LOCATION
8q13.1
LOCUSID
ALIAS
CISK,SGK2,SGKL
FUSION GENES

Other Information

Locus ID:

NCBI: 23678
MIM: 607591
HGNC: 10812
Ensembl: ENSG00000104205

Variants:

dbSNP: 23678
ClinVar: 23678
TCGA: ENSG00000104205
COSMIC: SGK3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104205ENST00000345714Q96BR1
ENSG00000104205ENST00000345714A0A024R807
ENSG00000104205ENST00000396596Q96BR1
ENSG00000104205ENST00000396596A0A024R807
ENSG00000104205ENST00000518388E5RK28
ENSG00000104205ENST00000519396E5RHR8
ENSG00000104205ENST00000520976Q96BR1
ENSG00000104205ENST00000521152E5RHY6
ENSG00000104205ENST00000521198Q96BR1
ENSG00000104205ENST00000521198A0A024R807
ENSG00000104205ENST00000521960E5RJV7
ENSG00000104205ENST00000522398Q96BR1
ENSG00000104205ENST00000522398A0A024R807
ENSG00000104205ENST00000522629E5RHX2

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
FoxO signaling pathwayKEGGhsa04068
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Stimuli-sensing channelsREACTOMER-HSA-2672351

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373988832023SGK3 overexpression correlates with a poor prognosis in endoscopically resected superficial esophageal squamous cell neoplasia: A long-term study.0
373988832023SGK3 overexpression correlates with a poor prognosis in endoscopically resected superficial esophageal squamous cell neoplasia: A long-term study.0
362691852022MicroRNA-92a-3p Regulates Retinal Angiogenesis by Targeting SGK3 in Vascular Endothelial Cells.3
362691852022MicroRNA-92a-3p Regulates Retinal Angiogenesis by Targeting SGK3 in Vascular Endothelial Cells.3
347403632021Circ_0043532 regulates miR-182/SGK3 axis to promote granulosa cell progression in polycystic ovary syndrome.8
347403632021Circ_0043532 regulates miR-182/SGK3 axis to promote granulosa cell progression in polycystic ovary syndrome.8
318214482020Mutation of SGK3, a Novel Regulator of Renal Phosphate Transport, Causes Autosomal Dominant Hypophosphatemic Rickets.5
324327322020MiR-377-3p inhibits cell metastasis and epithelial-mesenchymal transition in cervical carcinoma through targeting SGK3.7
326448522020Risk of Nasopharyngeal Carcinoma Associated with Single Nucleotide Polymorphisms in the MicroRNA Binding Site of SGK3.0
329264952020Phosphoinositide-dependent Kinase-1 (PDPK1) regulates serum/glucocorticoid-regulated Kinase 3 (SGK3) for prostate cancer cell survival.15
318214482020Mutation of SGK3, a Novel Regulator of Renal Phosphate Transport, Causes Autosomal Dominant Hypophosphatemic Rickets.5
324327322020MiR-377-3p inhibits cell metastasis and epithelial-mesenchymal transition in cervical carcinoma through targeting SGK3.7
326448522020Risk of Nasopharyngeal Carcinoma Associated with Single Nucleotide Polymorphisms in the MicroRNA Binding Site of SGK3.0
329264952020Phosphoinositide-dependent Kinase-1 (PDPK1) regulates serum/glucocorticoid-regulated Kinase 3 (SGK3) for prostate cancer cell survival.15
309751252019Functional role of SGK3 in PI3K/Pten driven liver tumor development.12

Citation

Dessen P

SGK3 (serum/glucocorticoid regulated kinase family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2011-04-01

Online version: http://atlasgeneticsoncology.org/gene/52187/sgk3-(serum-glucocorticoid-regulated-kinase-family-member-3)