Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3824
MIM: 602894
HGNC: 6378
Ensembl: ENSG00000134539
Variants:
dbSNP: 3824
ClinVar: 3824
TCGA: ENSG00000134539
COSMIC: KLRD1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10004 | adalimumab | Chemical | ClinicalAnnotation | associated | PD | 26453102 | |
| PA165107055 | certolizumab pegol | Chemical | ClinicalAnnotation | associated | PD | 26453102 | |
| PA443434 | Arthritis, Rheumatoid | Disease | ClinicalAnnotation | associated | PD | 26453102 | |
| PA449515 | etanercept | Chemical | ClinicalAnnotation | associated | PD | 26453102 | |
| PA450428 | methotrexate | Chemical | ClinicalAnnotation | associated | PD | 26453102 | |
| PA452347 | glucocorticoids | Chemical | ClinicalAnnotation | associated | PD | 26453102 | |
| PA452639 | infliximab | Chemical | ClinicalAnnotation | associated | PD | 26453102 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35924575 | 2023 | Early expression of CD94 and loss of CD96 on CD8+ T cells after allogeneic stem cell tranplantation is predictive of subsequent relapse and survival. | 1 |
| 35924575 | 2023 | Early expression of CD94 and loss of CD96 on CD8+ T cells after allogeneic stem cell tranplantation is predictive of subsequent relapse and survival. | 1 |
| 33615729 | 2021 | Reduced expansion of CD94/NKG2C(+) NK cells in chronic lymphocytic leukemia and CLL-like monoclonal B-cell lymphocytosis is not related to increased human cytomegalovirus seronegativity or NKG2C deletions. | 6 |
| 33887202 | 2021 | The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice. | 31 |
| 33990003 | 2021 | CD94 expression patterns in reactive and neoplastic T-cell and NK-cell proliferations. | 1 |
| 34271875 | 2021 | KLRD1, FOSL2 and LILRB3 as potential biomarkers for plaques progression in acute myocardial infarction and stable coronary artery disease. | 7 |
| 33615729 | 2021 | Reduced expansion of CD94/NKG2C(+) NK cells in chronic lymphocytic leukemia and CLL-like monoclonal B-cell lymphocytosis is not related to increased human cytomegalovirus seronegativity or NKG2C deletions. | 6 |
| 33887202 | 2021 | The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice. | 31 |
| 33990003 | 2021 | CD94 expression patterns in reactive and neoplastic T-cell and NK-cell proliferations. | 1 |
| 34271875 | 2021 | KLRD1, FOSL2 and LILRB3 as potential biomarkers for plaques progression in acute myocardial infarction and stable coronary artery disease. | 7 |
| 31409873 | 2020 | The inhibitory receptor CD94/NKG2A on CD8(+) tumor-infiltrating lymphocytes in colorectal cancer: a promising new druggable immune checkpoint in the context of HLAE/β2m overexpression. | 36 |
| 32569519 | 2020 | HLAs, TCRs, and KIRs, a Triumvirate of Human Cell-Mediated Immunity. | 40 |
| 32575403 | 2020 | NKG2A/CD94 Is a New Immune Receptor for HLA-G and Distinguishes Amino Acid Differences in the HLA-G Heavy Chain. | 14 |
| 31409873 | 2020 | The inhibitory receptor CD94/NKG2A on CD8(+) tumor-infiltrating lymphocytes in colorectal cancer: a promising new druggable immune checkpoint in the context of HLAE/β2m overexpression. | 36 |
| 32569519 | 2020 | HLAs, TCRs, and KIRs, a Triumvirate of Human Cell-Mediated Immunity. | 40 |
Citation
Dessen P
KLRD1 (killer cell lectin like receptor D1)
Atlas Genet Cytogenet Oncol Haematol. 2011-04-01
Online version: http://atlasgeneticsoncology.org/gene/52201/klrd1-(killer-cell-lectin-like-receptor-d1)
