Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27040
MIM: 602354
HGNC: 18874
Ensembl: ENSG00000213658
Variants:
dbSNP: 27040
ClinVar: 27040
TCGA: ENSG00000213658
COSMIC: LAT
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34924127 | 2022 | L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy. | 8 |
| 36205741 | 2022 | Identification of LAT/ZAP70 characterized immune subtypes of prostate cancer. | 0 |
| 34924127 | 2022 | L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy. | 8 |
| 36205741 | 2022 | Identification of LAT/ZAP70 characterized immune subtypes of prostate cancer. | 0 |
| 33458942 | 2021 | The role of prolines and glycine in the transmembrane domain of LAT. | 4 |
| 33562083 | 2021 | A Novel, LAT/Lck Double Deficient T Cell Subline J.CaM1.7 for Combined Analysis of Early TCR Signaling. | 4 |
| 33572370 | 2021 | Retrograde and Anterograde Transport of Lat-Vesicles during the Immunological Synapse Formation: Defining the Finely-Tuned Mechanism. | 1 |
| 33458942 | 2021 | The role of prolines and glycine in the transmembrane domain of LAT. | 4 |
| 33562083 | 2021 | A Novel, LAT/Lck Double Deficient T Cell Subline J.CaM1.7 for Combined Analysis of Early TCR Signaling. | 4 |
| 33572370 | 2021 | Retrograde and Anterograde Transport of Lat-Vesicles during the Immunological Synapse Formation: Defining the Finely-Tuned Mechanism. | 1 |
| 32727906 | 2020 | LRCH1 deficiency enhances LAT signalosome formation and CD8(+) T cell responses against tumors and pathogens. | 6 |
| 32979494 | 2020 | The membrane proximal proline-rich region and correct order of C-terminal tyrosines on the adaptor protein LAT are required for TCR-mediated signaling and downstream functions. | 1 |
| 32727906 | 2020 | LRCH1 deficiency enhances LAT signalosome formation and CD8(+) T cell responses against tumors and pathogens. | 6 |
| 32979494 | 2020 | The membrane proximal proline-rich region and correct order of C-terminal tyrosines on the adaptor protein LAT are required for TCR-mediated signaling and downstream functions. | 1 |
| 30637450 | 2019 | Significant relationship between the LAT1 expression pattern and chemoresistance in ovarian clear cell carcinoma. | 14 |
Citation
Dessen P
LAT (linker for activation of T cells)
Atlas Genet Cytogenet Oncol Haematol. 2011-05-01
Online version: http://atlasgeneticsoncology.org/gene/52202/lat-(linker-for-activation-of-t-cells)
