ULBP3 (UL16 binding protein 3)

2011-05-01  

Identity

HGNC
LOCATION
6q25.1
LOCUSID
ALIAS
N2DL-3,NKG2DL3,RAET1N

Other Information

Locus ID:

NCBI: 79465
MIM: 605699
HGNC: 14895
Ensembl: ENSG00000131019

Variants:

dbSNP: 79465
ClinVar: 79465
TCGA: ENSG00000131019
COSMIC: ULBP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131019ENST00000367339Q9BZM4
ENSG00000131019ENST00000438272Q9BZM4

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9

Pathways

PathwaySourceExternal ID
Natural killer cell mediated cytotoxicityKEGGko04650
Natural killer cell mediated cytotoxicityKEGGhsa04650
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
271424452016ULBP3: a marker for alopecia areata incognita.7
271424452016ULBP3: a marker for alopecia areata incognita.7
259952512015Varicella-Zoster Virus and Herpes Simplex Virus 1 Differentially Modulate NKG2D Ligand Expression during Productive Infection.26
259952512015Varicella-Zoster Virus and Herpes Simplex Virus 1 Differentially Modulate NKG2D Ligand Expression during Productive Infection.26
246775442014c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis.27
246775442014c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis.27
210480312011Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.5
213206922011An identical miRNA of the human JC and BK polyoma viruses targets the stress-induced ligand ULBP3 to escape immune elimination.86
216892462011Treatment of alopecia areata: "What is new on the horizon?".2
210480312011Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.5
213206922011An identical miRNA of the human JC and BK polyoma viruses targets the stress-induced ligand ULBP3 to escape immune elimination.86
216892462011Treatment of alopecia areata: "What is new on the horizon?".2
202196102010Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.10
202196102010Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.10
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37

Citation

Dessen P

ULBP3 (UL16 binding protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2011-05-01

Online version: http://atlasgeneticsoncology.org/gene/52222/ulbp3-(ul16-binding-protein-3)