Identity
HGNC
LOCATION
3p25.3
LOCUSID
ALIAS
C3orf10,HSPC300,MDS027,hHBrk1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55845
MIM: 611183
HGNC: 23057
Ensembl: ENSG00000254999
Variants:
dbSNP: 55845
ClinVar: 55845
TCGA: ENSG00000254999
COSMIC: BRK1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000254999 | ENST00000530758 | Q8WUW1 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 24680773 | 2014 | Sp1 transcriptionally regulates BRK1 expression in non-small cell lung cancer cells. | 4 |
| 24680773 | 2014 | Sp1 transcriptionally regulates BRK1 expression in non-small cell lung cancer cells. | 4 |
| 23939472 | 2013 | Novel genes FAM134C, C3orf10 and ENOX1 are regulated by NRF-1 and differentially regulate neurite outgrowth in neuroblastoma cells and hippocampal neurons. | 12 |
| 23939472 | 2013 | Novel genes FAM134C, C3orf10 and ENOX1 are regulated by NRF-1 and differentially regulate neurite outgrowth in neuroblastoma cells and hippocampal neurons. | 12 |
| 20861187 | 2010 | Brick1 is an essential regulator of actin cytoskeleton required for embryonic development and cell transformation. | 18 |
| 20861187 | 2010 | Brick1 is an essential regulator of actin cytoskeleton required for embryonic development and cell transformation. | 18 |
| 19576655 | 2009 | Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2. | 6 |
| 19764026 | 2009 | Genotype-phenotype correlations in VHL exon deletions. | 22 |
| 19764026 | 2009 | Genotype-phenotype correlations in VHL exon deletions. | 22 |
| 19576655 | 2009 | Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2. | 6 |
| 19764026 | 2009 | Genotype-phenotype correlations in VHL exon deletions. | 22 |
| 19764026 | 2009 | Genotype-phenotype correlations in VHL exon deletions. | 22 |
| 17311301 | 2007 | Loss of the actin regulator HSPC300 results in clear cell renal cell carcinoma protection in Von Hippel-Lindau patients. | 14 |
| 17311301 | 2007 | Loss of the actin regulator HSPC300 results in clear cell renal cell carcinoma protection in Von Hippel-Lindau patients. | 14 |
Citation
Dessen P
BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)
Atlas Genet Cytogenet Oncol Haematol. 2011-06-01
Online version: http://atlasgeneticsoncology.org/gene/52231/brk1-(brick1-subunit-of-scar-wave-actin-nucleating-complex)
